| Identification | More | [Name]
2',3'-O-ISOPROPYLIDENEURIDINE | [CAS]
362-43-6 | [Synonyms]
2',3'-IPU
2',3'-ISOPROPYLIDENEURIDENE
2,3-ISOPROPYLIDENE URIDINE
2',3'-ISOPROPYLIDENEURIDINE
2',3'-O-ISOPROPYLIDENEURIDINE
Uridine 2',3'-acetonide
Uridine, 2',3'-O-(1-methylethylidene)-
Uridine, 2',3'-O-isopropylidene-
2'.3'-Isopropylidene-Uridine,>99%
2',3'-O-Isopropylidene-D-uridine
2'-O,3'-O-Isopropylideneuridine | [EINECS(EC#)]
206-647-7 | [Molecular Formula]
C12H16N2O6 | [MDL Number]
MFCD00034509 | [Molecular Weight]
284.27 | [MOL File]
362-43-6.mol |
| Chemical Properties | Back Directory | [Appearance]
White Needle-Like Crystals | [Melting point ]
163-166 °C | [Boiling point ]
426.76°C (rough estimate) | [density ]
1.2932 (rough estimate) | [refractive index ]
1.5460 (estimate) | [storage temp. ]
-20°C | [solubility ]
Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly) | [form ]
Fine Crystalline Powder or Needles | [pka]
9.25±0.10(Predicted) | [color ]
White | [biological source]
synthetic (organic) | [Water Solubility ]
water: 50mg/mL, clear to very slightly hazy, colorless to light yellow | [Usage]
A useful precursor for the preparation of nucleic acids | [BRN ]
32671 | [InChI]
InChI=1S/C12H16N2O6/c1-12(2)19-8-6(5-15)18-10(9(8)20-12)14-4-3-7(16)13-11(14)17/h3-4,6,8-10,15H,5H2,1-2H3,(H,13,16,17)/t6-,8-,9-,10-/m1/s1 | [InChIKey]
GFDUSNQQMOENLR-PEBGCTIMSA-N | [SMILES]
OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@@H]2OC(O[C@H]12)(C)C | [CAS DataBase Reference]
362-43-6(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Description]
2',3'-Isopropylideneuridine has been shown to inhibit binding of pestivirus inhibitors by monoclonal antibodies. 2',3'-Isopropylideneuridine was also found to inhibit the replication of human immunodeficiency virus (HIV) in tissue culture by binding to the viral RNA polymerase and inhibiting its activity, preventing viral replication. | [Chemical Properties]
White Needle-Like Crystals | [Uses]
2′,3′-O-Isopropylideneuridine is used in the chemical synthesis of N-benzoylated uridine derivatives and N3-substituted 2′,3′-O-isopropylideneuridines with central nervous system (CNS) depressant activity. | [Uses]
2',3'-O-Isopropylideneuridine can be used as a useful precursor for the preparation of nucleic acids.
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