| Identification | More | [Name]
6-Aminonicotinic acid | [CAS]
3167-49-5 | [Synonyms]
2-AMINO-5-PYRIDINECARBOXYLIC ACID
2-AMINOPYRIDINE-5-CARBOXYLIC ACID
6-AMINONICOTINIC ACID
6-AMINOPYRIDINE-3-CARBOXYLIC ACID
RARECHEM AL BO 1167
TIMTEC-BB SBB004186
3-Pyridinecarboxylic acid, 6-amino-
6-amino-3-pyridinecarboxylicaci
2-Amino-5-carboxypyridine
6-Amino-3-pyridinecaboxylic acid
6-Aminonicotinic acid
6-Aminopyridine-3-carboxylic acid
6-AMINO-3-PYRIDINE CARBOXLIC ACID
6-Aminonicotinic acid, 98+%
6-Aminonicotinic acid 98%
3-Pyridinecarboxylicacid,6-amino-(9CI)
2-Aminopyridine-5-carboxylic acid(6-Aminonicotinic acid)
6-Amino-3-pyridinecarboxylic Acid | [EINECS(EC#)]
221-630-4 | [Molecular Formula]
C6H6N2O2 | [MDL Number]
MFCD00006326 | [Molecular Weight]
138.12 | [MOL File]
3167-49-5.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,T | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [TSCA ]
T | [HazardClass ]
IRRITANT | [HS Code ]
29333990 |
| Hazard Information | Back Directory | [Chemical Properties]
Light yellow Cryst | [Uses]
Antiproliferative | [Application]
6-Aminonicotinic acid is an inhibitor of bacterial DNA gyrase and topoisomerase IV. It has been shown to inhibit the growth of a number of bacteria, including E. coli K-12, with potent inhibitory activity against these enzymes. It binds to the active sites on these enzymes and prevents them from working. The detection time for 6-aminonicotinic acid is about 3 hours after exposure. It has been shown to be more potent than other inhibitors of bacterial DNA gyrase and topoisomerase IV such as 2,4-diaminopyrimidine (2,4DAP). | [Definition]
ChEBI: An aminonicotinic acid in which the amino group is situated at position 6 of the pyridine ring. | [General Description]
Electrosynthesis of 6-aminopyridine-3-carboxylic acid (6-aminonicotinic acid) by electrochemical reduction of 2-amino-5-bromo and 2-amino-5-chloropyridine in the presence of CO2 at silver electrode has been reported. | [Purification Methods]
Crystallise the acid from aqueous acetic acid. Dry it in vacuo at 70o. [Beilstein 22 III/IV 6726.] |
|
|