| Identification | More | [Name]
1-Aminohydantoin hydrochloride | [CAS]
2827-56-7 | [Synonyms]
1-AMINO-2,4-IMIDAZOLIDINEDIONE HCL
1-AMINO-2,4-IMIDAZOLIDIONE HCL
1-AMINOHYDANTOIN HCL
1-AMINOHYDANTOIN HYDROCHLORIDE
1-AMINO-IMIDAZOLIDINE-2,4-DIONE HYDROCHLORIDE
TIMTEC-BB SBB004061
1-Amino-2,4-Imidazolinedione
1-Aminoimidazoline-2,4-dione hydrochloride
1-Aminohydantoin Hydrochloride, Vetranal
1-Aminohydantoine
1-AMINO-2,4-IMIDAZOLIDINEDIONE HYDROCHLORIDE
1-Amino-imidazolidine-2,4-dione Hydrochlorid
ahd | [Molecular Formula]
C3H6ClN3O2 | [MDL Number]
MFCD02181047 | [Molecular Weight]
151.55 | [MOL File]
2827-56-7.mol |
| Chemical Properties | Back Directory | [Appearance]
Pale Yellow Powder | [Melting point ]
201-205 °C(lit.)
| [storage temp. ]
0-6°C | [solubility ]
DMSO (Slightly), Methanol (Slightly, Heated) | [form ]
Crystalline Powder | [color ]
Pale yellow | [biological source]
mouse | [BRN ]
3699376 | [Stability:]
Unstable in Solution | [CAS DataBase Reference]
2827-56-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [HS Code ]
29332100 |
| Hazard Information | Back Directory | [Chemical Properties]
Pale Yellow Powder | [Uses]
A metabolite of Nitrofuran. | [Uses]
Reactant for synthesis of: Ectoparasiticidal drugs1 Skeletal muscle relaxants2Reactant for: Suzuki-Miyaura coupling3 Lymphoid specific tryosine phosphatase inhibitor4 Proteasome inhibition by peptide semicarbazones5 | [Biological Activity]
Tumor Necrosis Factor (TNF)-Related Apoptosis-Inducing Ligand (TRAIL) activates the extrinsic apoptotic pathway by binding death receptors (DR) 4 and 5. In addition to DR 4 and 5TRAIL activates several other receptors such as decoy receptor (DcR)1DcR2 and a soluble receptor called osteoprotegerin. TRAIL plays a vital role in the inhibition of autoimmune inflammation and cell cycle progression. TRAIL selectively kills tumor cells without damaging normal tissues and thereforeit might act as a tumor-selective anticancer agent. TRAIL-induced apoptosis is involved in various cellular processes including activation-induced cell deathhomeostasisintrathymic negative selectionautoimmunity suppressionand immune surveillance. Repeated dosage of recombinant soluble TRAIL triggers apoptosisinhibits tumor progressionand increases viability of mice suffering from cancer. |
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