Identification | Back Directory | [Name]
Liensinine | [CAS]
2586-96-1 | [Synonyms]
LIENSININE Hiensinine Liensinine USP/EP/BP Liensinine perchlorafe Phenol,4-[[(1R)-1,2,3,4-tetrahydro-6, 7-dimethoxy- 2-methyl-1-isoquinolinyl]methyl]-2-[[(1R)-1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-7-isoquinolinyl]oxy]- 4-[[(1R)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-[[(1R)-1-(4-hydroxybenzyl)-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]phenol 4-[[(1r)-6,7-dimethoxy-2-methyl-3,4-dihydro-1h-isoquinolin-1-yl]methyl]-2-[[(1r)-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1h-isoquinolin-7-yl]oxy]phenol Phenol, 4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[[(1R)-1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-7-isoquinolinyl]oxy]- Liensinine
4-[[(1R)-6,7-Dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-[[(1R)-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]phenol | [EINECS(EC#)]
683-151-0 | [Molecular Formula]
C37H42N2O6 | [MDL Number]
MFCD03427702 | [MOL File]
2586-96-1.mol | [Molecular Weight]
610.74 |
Chemical Properties | Back Directory | [Melting point ]
95-99 °C | [Boiling point ]
722.0±60.0 °C(Predicted) | [density ]
1.218±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
Acetone (Slightly), Chloroform (Slightly) | [form ]
Solid | [pka]
9.28±0.45(Predicted) | [color ]
White to Off-White |
Hazard Information | Back Directory | [Description]
The isomer of isoliensinine (q.v.), this alkaloid is present in the embryo of the
seeds of Nelumbo nucifera Gaertn. | [Uses]
Liensinine is a bisbenzylisoquinoline alkaloid with inhibitory properties towards the activation of microglial cells. In testing with rats, iensinine decreased epileptic discharges were observed on electrocorticograms. | [Definition]
ChEBI: Liensinine is a member of isoquinolines. | [References]
Tse-yuan et al., Sci. Sinica., 11, 215 (1962)
Pei-chuanetal., ibid, 11,321 (1962) |
|
|