| Identification | Back Directory | [Name]
Homo-PROTAC pVHL30 degrader 1 | [CAS]
2244684-49-7 | [Synonyms]
CM11 (Homo-PROTAC)
CM11 VHL inhibitor
Homo-PROTAC pVHL30 degrader 1 | [Molecular Formula]
C58H82N8O14S2 | [MDL Number]
MFCD31656712 | [MOL File]
2244684-49-7.mol | [Molecular Weight]
1179.46 |
| Chemical Properties | Back Directory | [Boiling point ]
1293.3±65.0 °C(Predicted) | [density ]
1.266±0.06 g/cm3(Predicted) | [storage temp. ]
4°C, stored under nitrogen | [solubility ]
DMSO : ≥ 150 mg/mL (127.18 mM) | [form ]
Solid | [pka]
13.24±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Homo-PROTAC pVHL30 degrader 1 is a potent pVHL30 degrader based on PROTAC[1], consists of two ligands of von Hippel-Lindau. | [IC 50]
VHL | [storage]
Store at -20°C | [References]
[1] Maniaci C, et al. Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat Commun. 2017 Oct 10;8(1):830. DOI:10.1038/s41467-017-00954-1 |
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| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Website: |
http://m.is0513.com/ShowSupplierProductsList927327/0.htm |
| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
|