Identification | Back Directory | [Name]
Halo PROTAC 1 | [CAS]
2241668-45-9 | [Synonyms]
Halo PROTAC 1 Propanamide, 2-(acetylamino)-3-[[2-amino-9-[(4-chlorophenyl)methyl]-6,9-dihydro-6-oxo-1H-purin-8-yl]thio]-N-(21-chloro-3,6,9,12,15-pentaoxaheneicos-1-yl)-, (2R)- | [Molecular Formula]
C33H49Cl2N7O8S | [MDL Number]
MFCD32263229 | [MOL File]
2241668-45-9.mol | [Molecular Weight]
774.76 |
Hazard Information | Back Directory | [Uses]
HaloAUTAC tt15 is an autophagy-targeting chimera (AUTAC), that targets the Halo Tag carrying proteins, and degrades via the autophagy mechanism[1]. | [References]
[1] Takahashi D, et al., Second-Generation AUTACs for Targeted Autophagic Degradation. J Med Chem. 2023 Sep 14;66(17):12342-12372. DOI:10.1021/acs.jmedchem.3c00861 |
|
|