| Identification | Back Directory | [Name]
eupatilin | [CAS]
22368-21-4 | [Synonyms]
eupatilin
NSC 122413
Eupatilin, BR
Eupatilin 22368-21-4
5,7-Dihydroxy-3',4',6-trimethoxyflavone
2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxychromen-4-one
2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxy-4H-chromen-4-one
2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxy-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 2-(3,4-diMethoxyphenyl)-5,7-dihydroxy-6-Methoxy-
Eupatilin
2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxychromen-4-one
2-(3,4-dimethoxyphenyl)-5,7-dihydroxy-6-methoxy-4H-chromen-4-one (EUPATILIN) | [EINECS(EC#)]
618-347-7 | [Molecular Formula]
C18H16O7 | [MDL Number]
MFCD13194819 | [MOL File]
22368-21-4.mol | [Molecular Weight]
344.31 |
| Chemical Properties | Back Directory | [Melting point ]
236-238 °C | [Boiling point ]
583.6±50.0 °C(Predicted) | [density ]
1.387±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Store in freezer, under -20°C | [solubility ]
Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly, Heated) | [form ]
Solid | [pka]
6.47±0.40(Predicted) | [color ]
Pale Beige | [biological source]
(Isolated from Artemisia sp.) | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
Eupatilin maintains anticoagulant and antiplatelet activity isolated from the Artemisia princeps Pampanini flower. | [Definition]
ChEBI: A trimethoxyflavone with flavone substituted by hydroxy groups at C-5 and C-7 and methoxy groups at C-6, C-3' and C-4' respectively. Isolated from Citrus reticulata and Salvia tomentosa, it exhibits anti-inflammatory, anti-ulcer a
d antineoplastic activities. | [Biological Activity]
Eupatilin is a flavone with anti-oxidativeanti-inflammatoryand anti-cancer properties.''Eupatilin is an important constituent in the leaves of Artemisia argyi and also an active component of DA-9601. It exhibits anti-apoptotic effects. Eupatilin provides protection against tumor necrosis factor α (TNF-α)-mediated inflammation in human umbilical vein endothelial cells. It is used in the treatment of gastritis and peptic ulcers. Eupatilin safeguards gastric epithelial cells from oxidative damage and smooth muscle cells from indomethacin-induced cell damage. Eupatilin lowers bile acid-stimulated hepatocyte apoptosis. | [storage]
+4°C |
|
|