Identification | Back Directory | [Name]
Hydrocortisone 21-hemisuccinate | [CAS]
2203-97-6 | [Synonyms]
C12888 saxizon NSC 7576 -2-oxoethoxy) cortisolsuccinate Hydrocortisone 21-he CORTISOL HEMISUCCINATE Hydrocortizone Succinate HYDROCORTISONE SUCCINATE CORTISOL 21-HEMISUCCINATE 20-dione 21-hemisuccinate 21-Trihydroxy-4-pregnene-3 cortisol,hydrogensuccinate HYDROXYCORTISONE SUCCINATE hydrocortisone21-succinate Hydrocortisone Succinate RS HYDROCORTISONE HEMISUCCINATE HYDROCORTISONE 21-HEMISUCCINATE cortisol,21-(hydrogensuccinate) HYDROCORTISONE HYDROGEN SUCCINATE 4-(2-((8S,9S,10R,11S,13S,14S,17R) Hydrocortisone acetate half Kohaku Cortisol, hydrogen succinate (7CI) Hydrocortisone hydrogen succinate CRS hydrocortisone 21-(hydrogen succinate) HYDROCORTISONEHEMISUCCINATE(ANHYDROUS) Cortisol 21-(4-oxo-4-hydroxybutanoate) Cortisol, 21-(hydrogen succinate) (8CI) hydrocortisone 21-hemisuccinate*free acid Hydrocortisone 21-hemisuccinate USP/EP/BP 4-PREGNEN-11-BETA, 17,21-TRIOL-3,20-DIONE 21-HEMISUCCINATE 11β,17α,21-trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate 11b,17a,21-Trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate 4-PREGNEN-11BETA,17ALPHA,21-TRIOL-3,20-DIONE 21-HEMISUCCINATE 21-(3-Carboxy-1-oxopropoxy)-11β,17-dihydroxypregn-4-ene-3,20-dione 21-(3-Carboxy-1-oxopropoxy)-11β,17α-dihydroxypregn-4-ene-3,20-dione 11BETA,17ALPHA,21-TRIHYDROXY-4-PREGNENE-3,20-DIONE 21-HEMISUCCINATE 11beta,17,21-Trihydroxypregn-4-ene-3,20-dione21-(hydrogensuccinate) 17-dihydroxy-20-dion(11-beta)-preg-4-ene-21-(3-carboxy-1-oxopropoxy)-11 (11-beta)-21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxypreg-4-ene-3,20-dione Pregn-4-ene-3,20-dione,21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-, (11b)- Pregn-4-ene-3,20-dione, 21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-, (11β)- -11,17-Dihydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl) 4-[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid 4-(2-((8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethoxy)-4-oxobutanoic acid | [EINECS(EC#)]
218-612-3 | [Molecular Formula]
C25H34O8 | [MDL Number]
MFCD00046256 | [MOL File]
2203-97-6.mol | [Molecular Weight]
462.53 |
Chemical Properties | Back Directory | [Appearance]
White or almost white, hygroscopic powder | [Melting point ]
170~172℃ | [alpha ]
[α]D20 +147~+153° (c=1, C2H5OH) (After Drying) | [Boiling point ]
685.5±55.0 °C(Predicted) | [density ]
1.33±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
Practically insoluble in water, freely soluble in acetone and in anhydrous ethanol. It dissolves in dilute solutions of alkali carbonates and alkali hydroxides. | [form ]
neat | [pka]
pKa 5.10/5.64(20% aq EtOH/50% aq EtOH) (Uncertain) | [color ]
White to Off-White |
Hazard Information | Back Directory | [Chemical Properties]
White or almost white, hygroscopic powder | [Uses]
glucocorticoid | [Definition]
ChEBI: A derivative of succinic acid in which one of the carboxy groups is esterified by the C-21 hydroxy group of cortisol (hydrocortisone). | [Brand name]
A-Hydrocort (Abbott); A-Hydrocort (Hospira); Solu-Cortef
(Pharmacia & Upjohn). |
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