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ChemicalBook--->CAS DataBase List--->2055041-38-6

2055041-38-6

2055041-38-6 Structure

2055041-38-6 Structure
IdentificationBack Directory
[Name]

Mal-PEG2-Val-Cit-amido-PAB-OH
[CAS]

2055041-38-6
[Synonyms]

Mal-PEG2-Val-Cit-PAB-OH
Mal-PEG2-Val-Cit-amido-PAB-OH
[Molecular Formula]

C29H42N6O9
[MDL Number]

MFCD29918233
[MOL File]

2055041-38-6.mol
[Molecular Weight]

618.68
Chemical PropertiesBack Directory
[solubility ]

Soluble in DMSO, DMF
Hazard InformationBack Directory
[Description]

Mal-PEG2-Val-Cit-PAB-OH is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. The maleimide group is reactive toward thiol groups between pH 6.5 to 7.5. PEG chain increases the water solubility of the compound.
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