| Identification | Back Directory | [Name]
9-methoxycamptothecin | [CAS]
19685-10-0 | [Synonyms]
product/154918
9-methoxycamptothecin
10-MethoxycaMptothecine
(4S)-4-Ethyl-4-hydroxy-9-methoxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
(4S)-9-Methoxy-4α-ethyl-4β-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,4-ethyl-4-hydroxy-9-methoxy-, (4S)- | [EINECS(EC#)]
2017-001-1 | [Molecular Formula]
C21H18N2O5 | [MOL File]
19685-10-0.mol | [Molecular Weight]
378.38 |
| Chemical Properties | Back Directory | [Melting point ]
254-255℃ | [Boiling point ]
773.1±60.0 °C(Predicted) | [density ]
1.50 | [storage temp. ]
4°C, protect from light | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Cryst. | [pka]
11.21±0.20(Predicted) | [color ]
White to yellow |
| Hazard Information | Back Directory | [Description]
A minor constituent of Mappia foetida Miers. The alkaloid yields pale yellow
crystals when purified from CHC13-MeOH. It is laevorotatory with [α]24D -
77.5° (c 1.0, pyridine). The structure has been established by spectroscopic
methods. | [Uses]
10-Methoxycamptothecin is a Camptothecin (C175150) derivative used in the treatment of cancers. Used in the treatment of hyperproliferative diseases. | [References]
Govindachari, Viswanathan., Phytochem., 11, 3529 (1972)
Govindachari, Viswanathan.,Ind. J. Chem., 10,453 (1972) |
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