| Identification | Back Directory | [Name]
Acid-PEG4-t-butyl ester | [CAS]
1835759-85-7 | [Synonyms]
COOH-PEG4-OtBu
COOH-PEG4-COOtBu
Acid-PEG4-C2-Boc
Acid-PEG4-t-butyl ester
HOOCCH2CH2O-PEG3-CH2CH2COOtBu
Di-tert-butyl 4,7,10,13-tetraoxahexadecane-1,16-dioate
2,2-Dimethyl-4-oxo-3,7,10,13,16-pentaoxanonadecan-19-oic acid
4,7,10,13-Tetraoxahexadecanedioic acid, 1-(1,1-dimethylethyl) ester | [Molecular Formula]
C20H38O8 | [MDL Number]
MFCD29042335 | [MOL File]
1835759-85-7.mol | [Molecular Weight]
350.4 |
| Chemical Properties | Back Directory | [Boiling point ]
460.1±40.0 °C(Predicted) | [density ]
1.107±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Water, DMSO, DCM, DMF | [form ]
Liquid | [pka]
4.28±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
Acid-PEG4-t-butyl ester is a PEG linker containing a t-butyl protected carboxyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. |
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