| Identification | Back Directory | [Name]
Ald-Ph-PEG6-t-butyl ester | [CAS]
2055013-49-3 | [Synonyms]
Ald-Ph-PEG6-Boc
CHO-Ph-PEG6-COOtBu
Ald-Ph-PEG6-COOtBu
CHO-Ph-CONH-PEG6-COOtBu
Ald-Ph-PEG6-t-butyl ester
4,7,10,13,16,19-Hexaoxa-22-azatricosanoic acid, 23-(4-formylphenyl)-23-oxo-, 1,1-dimethylethyl ester | [Molecular Formula]
C27H43NO10 | [MDL Number]
MFCD28155204 | [MOL File]
2055013-49-3.mol | [Molecular Weight]
541.63 |
| Hazard Information | Back Directory | [Description]
Ald-Ph-PEG6-t-butyl ester is reactive with aminooxy containing molecules. The t-butyl ester is acid labile. The hydrophilic PEG linker increases the water solubility of the compound. | [Uses]
Ald-Ph-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs; Alkyl/ether | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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