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ChemicalBook--->CAS DataBase List--->1807537-42-3

1807537-42-3

1807537-42-3 Structure

1807537-42-3 Structure
IdentificationBack Directory
[Name]

Mal-PEG5-NHS ester
[CAS]

1807537-42-3
[Synonyms]

Mal-PEG5-NHS
Mal-PEG5-NHS ester
[Molecular Formula]

C21H30N2O11
[MDL Number]

MFCD26127781
[MOL File]

1807537-42-3.mol
[Molecular Weight]

486.47
Chemical PropertiesBack Directory
[Boiling point ]

608.4±65.0 °C(Predicted)
[density ]

1.34±0.1 g/cm3(Predicted)
[solubility ]

Soluble in DMSO, DCM, DMF
[form ]

Liquid
[pka]

-2.34±0.20(Predicted)
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Description]

Mal-PEG5-NHS ester is a PEG linker containing a maleimide group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
[Uses]

Mal-PEG5-NHS ester is an Alkyl/ether and PEG-based PROTAC linker can be used in the synthesis of PROTACs.
[IC 50]

PEGs; Alkyl/ether
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