Identification | Back Directory | [Name]
alpha-MaleiMidopropionyl-oMega-succiniMidyl-6(ethylene glycol) | [CAS]
1137109-21-7 | [Synonyms]
SM(PEG)6 Mal-PEG6-NHS Mal-NH-PEG6-NHS Mal-amido-PEG6-NHS MAL-dPEG??-NHS ester Maleimide-(PEG)6-NHS MAL-NH-PEG6-CH2CH2COONHS Maleimide-PEG6-NHS ester Mal-amido-PEG6-NHS ester Maleimide-PEG6-succinimidyl ester Maleimide-NH-PEG6-CH2CH2COONHS Ester PEGylated, long-chain SMCC crosslinker Maleimidopropionyl-PEG6-CH2CH2COONHS Ester α-MaleiMidopropionyl-ω-succiniMidyl-6(ethylene glycol) alpha-MaleiMidopropionyl-oMega-succiniMidyl-6(ethylene glycol) 3-(2-Maleimidoethylcarbonyl)amino(peg6)propionic acid N-Hydroxysuccinimide ester 2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16,19,22-hexaoxa-4-azapentacosan-25-oate 25-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-23-oxo-4,7,10,13,16,19-hexaoxa-22-azapentacosanoic acid 2,5-dioxo-1-pyrrolidinyl ester 4,7,10,13,16,19-Hexaoxa-22-azapentacosanoic acid, 25-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-23-oxo-, 2,5-dioxo-1-pyrrolidinyl ester | [Molecular Formula]
C26H39N3O13 | [MDL Number]
MFCD11041093 | [MOL File]
1137109-21-7.mol | [Molecular Weight]
601.6 |
Chemical Properties | Back Directory | [Melting point ]
54 - 57°C | [density ]
1.32±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
Acetonitrile (Slightly), Water (Slightly) | [form ]
Solid | [pka]
15.01±0.46(Predicted) | [color ]
White to Off-White |
Hazard Information | Back Directory | [Description]
Mal-amido-PEG6-NHS is a PEG linker containing a maleimide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. | [Uses]
Heterobifunctional crosslinker with an ethylene oxide spacer for linking amine- to sulfhydryl-containing compounds or biomolecules. Maleimide functional group will react with sulfhydryls and the succinimidyl ester group will react with amines. Spacer length is 31.7 angstroms. |
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