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ChemicalBook--->CAS DataBase List--->1137109-21-7

1137109-21-7

1137109-21-7 Structure

1137109-21-7 Structure
IdentificationBack Directory
[Name]

alpha-MaleiMidopropionyl-oMega-succiniMidyl-6(ethylene glycol)
[CAS]

1137109-21-7
[Synonyms]

SM(PEG)6
Mal-PEG6-NHS
Mal-NH-PEG6-NHS
Mal-amido-PEG6-NHS
MAL-dPEG??-NHS ester
Maleimide-(PEG)6-NHS
MAL-NH-PEG6-CH2CH2COONHS
Maleimide-PEG6-NHS ester
Mal-amido-PEG6-NHS ester
Maleimide-PEG6-succinimidyl ester
Maleimide-NH-PEG6-CH2CH2COONHS Ester
PEGylated, long-chain SMCC crosslinker
Maleimidopropionyl-PEG6-CH2CH2COONHS Ester
α-MaleiMidopropionyl-ω-succiniMidyl-6(ethylene glycol)
alpha-MaleiMidopropionyl-oMega-succiniMidyl-6(ethylene glycol)
3-(2-Maleimidoethylcarbonyl)amino(peg6)propionic acid N-Hydroxysuccinimide ester
2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16,19,22-hexaoxa-4-azapentacosan-25-oate
25-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-23-oxo-4,7,10,13,16,19-hexaoxa-22-azapentacosanoic acid 2,5-dioxo-1-pyrrolidinyl ester
4,7,10,13,16,19-Hexaoxa-22-azapentacosanoic acid, 25-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-23-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
[Molecular Formula]

C26H39N3O13
[MDL Number]

MFCD11041093
[MOL File]

1137109-21-7.mol
[Molecular Weight]

601.6
Chemical PropertiesBack Directory
[Melting point ]

54 - 57°C
[density ]

1.32±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C
[solubility ]

Acetonitrile (Slightly), Water (Slightly)
[form ]

Solid
[pka]

15.01±0.46(Predicted)
[color ]

White to Off-White
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P280-P302+P352-P362+P364
[WGK Germany ]

3
[HS Code ]

2928009090
Hazard InformationBack Directory
[Description]

Mal-amido-PEG6-NHS is a PEG linker containing a maleimide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
[Uses]

Heterobifunctional crosslinker with an ethylene oxide spacer for linking amine- to sulfhydryl-containing compounds or biomolecules. Maleimide functional group will react with sulfhydryls and the succinimidyl ester group will react with amines. Spacer length is 31.7 angstroms.
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