Identification | Back Directory | [Name]
Mal-Amido-PEG4-acid | [CAS]
1263045-16-4 | [Synonyms]
Mal-NH-PEG4-COOH Mal-NH-PEG4-acid Mal-Amido-PEG4-acid MAL-AMIDO-PEG4-COOH Maleimide-NH-PEG4-CH2CH2COOH Maleimide-PEG4-propionic acid Mal-amido-PEG4-propionic acid Mal-CH2CH2CONH-PEG4-CH2CH2COOH 19-Maleimido-17-oxo-4,7,10,13-tetraoxa-16-azanonadecanoic Acid 1-Maleimido-3-oxo-7,10,13,16-tetraoxa-4-azanonadecan-19-oic Acid 4,7,10,13-Tetraoxa-16-azanonadecanoic acid, 19-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-17-oxo- 1-[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido]-3,6,9,12-tetraoxapentadecan-15-oic acid | [Molecular Formula]
C18H28N2O9 | [MDL Number]
MFCD13184954 | [MOL File]
1263045-16-4.mol | [Molecular Weight]
416.42 |
Chemical Properties | Back Directory | [Boiling point ]
659.1±55.0 °C(Predicted) | [density ]
1.270±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Water, DMSO, DMF, DCM | [form ]
powder to crystal | [pka]
4.28±0.10(Predicted) | [color ]
White to Gray to Brown | [CAS DataBase Reference]
1263045-16-4 |
Hazard Information | Back Directory | [Description]
Mal-amido-PEG4-acid is a PEG linker containing a maleimide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. |
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