| Identification | Back Directory | [Name]
bpV(phen) (potassium hydrate) | [CAS]
171202-16-7 | [Synonyms]
bpV(phen) trihydrate
bpV(phen) (potassium hydrate)
Bisperoxovanadium
(Bisperoxovanadium(phen) | [Molecular Formula]
C12H14KN2O8V | [MDL Number]
MFCD28053521 | [MOL File]
171202-16-7.mol | [Molecular Weight]
404.288 |
| Hazard Information | Back Directory | [Description]
bpV(phen) is a bisperoxovanadium (bpV) compound which inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 = 38 nM). It also inhibits the vascular endothelial PTP, PTP-β (IC50 = 343 nM), and PTP-1β (IC50 = 920 nM). At 0.1 mM, bpV(phen) inhibits SH2 domain-containing inositol 5’-phosphatase-2. Presumably by inhibiting insulin receptor kinase-associated PTPs, bpV(phen) activates the insulin receptor tyrosine kinase and promotes downstream signaling, including activation of PI3-kinase. | [Uses]
bpV(phen) (Potassium Hydrate) inhibits several different protein tyrosine phosphatases (PTPs). | [storage]
Store at -20°C |
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| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
MedChemExpress
|
| Tel: |
021-58955995 |
| Website: |
www.medchemexpress.com |
|