| Identification | More | [Name]
Metaxalone | [CAS]
1665-48-1 | [Synonyms]
5-[(3,5-dimethylphenoxy)methyl]oxazolidin-2-one
METAXALONE
METAXALONE-D6
METAXOLONE
SKELAXIN
2-Oxazolidinone, 5-((3,5-xylyloxy)methyl)-
2-Oxazolidinone, 5-[(3,5-dimethylphenoxy)methyl]-
5-((3,5-dimethylphenoxy)methyl)-2-oxazolidinon
5-((3,5-Dimethylphenoxy)methyl)-2-oxazolidinone
5-((3,5-xylyloxy)methyl)-2-oxazolidinon
5-((3,5-Xylyloxy)methyl)-2-oxazolidinone
5-(3,5-Xyloloxymethyl)oxazolidin-2-one
5-[(3,5-Dimethylphenoxy)methyl]-1,3-oxazolidin-2-one
AHR-438
CL 39,148
cl39,148
Metaxalon
Metazalone
Metazolone
Methaxalonum | [EINECS(EC#)]
216-777-6 | [Molecular Formula]
C12H15NO3 | [MDL Number]
MFCD00867700 | [Molecular Weight]
221.25 | [MOL File]
1665-48-1.mol |
| Hazard Information | Back Directory | [Chemical Properties]
White Crystalline Solid | [Originator]
Skelaxin,Robins,US,1962 | [Uses]
For the treatment of painful peripheral musculoskeletal conditions and spasticity from upper motor neuron syndromes. | [Uses]
It is a muscle relaxant used to relax muscles and relieve pain | [Uses]
Metaxalone is a skeletal muscle relaxant that has applications in reducing muscle spasm, limitations in normal motion, and pain caused by musculoskeletal conditions. It is commonly used in combination with analgesics to address low back pain. The molecular or cellular actions of metaxalone is not known.[Cayman Chemical] | [Uses]
muscle relaxant (skeletal) | [Definition]
ChEBI:Metaxalone is an aromatic ether. | [Manufacturing Process]
Urea (118 g, 1.96 mols) was added to 192 g (0.98 mol) of 3-(3',5'- dimethylphenoxy)-1,2-propane-diol which had previously been heated to 150°C. The reaction mixture was then heated rapidly to 195° to 200°C and maintained at this temperature for 5 hours with constant stirring. The resulting mixture was partitioned between water and ethyl acetate and the ethyl acetate layer was dried over sodium sulfate and concentrated. The residue was distilled in vacuo and the fraction boiling at 220° to 225°C/1.5 mm was collected. Yield, 172 g (79%). The distillate was crystallized from dry ethyl acetate; MP, 121.5° to 123°C. | [Therapeutic Function]
Muscle relaxant | [storage]
Store at -20°C |
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