| Identification | More | [Name]
ETHOXYCARBONYL ISOTHIOCYANATE | [CAS]
16182-04-0 | [Synonyms]
CARBETHOXYISOTHIOCYANATE
CARBON(ISOTHIOCYANATIDIC)ACID, ETHYL ESTER
ETHOXYCARBONYL ISOTHIOCYANATE
ETHYL ISOTHIOCYANATOFORMATE
ISOTHIOCYANATOFORMIC ACID ETHYL ESTER
Ethyl isothiocyanatidocarbonate
ETHYL ISOTHIOCYANATOFORMATE,98%
(Ethoxyoxomethyl) isothiocyanate
Ethoxy(oxo)methyl isothiocyanate
Isothiocyanatoformic acid ethyl
Isothiocyanoformic acid ethyl ester | [EINECS(EC#)]
240-318-9 | [Molecular Formula]
C4H5NO2S | [MDL Number]
MFCD00004814 | [Molecular Weight]
131.15 | [MOL File]
16182-04-0.mol |
| Chemical Properties | Back Directory | [Appearance]
Light Yellow Oil | [Boiling point ]
56 °C18 mm Hg(lit.) | [density ]
1.112 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.500(lit.)
| [Fp ]
123 °F
| [storage temp. ]
2-8°C
| [solubility ]
Soluble in chloroform and ether. | [Specific Gravity]
1.112 | [Sensitive ]
Moisture Sensitive/Lachrymatory | [BRN ]
606091 | [InChIKey]
BDTDECDAHYOJRO-UHFFFAOYSA-N | [Uses]
Versatile reagent for organic synthesis. | [CAS DataBase Reference]
16182-04-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
T,Xi | [Risk Statements ]
R23:Toxic by inhalation.
R36/37/38:Irritating to eyes, respiratory system and skin .
R42:May cause sensitization by inhalation. | [Safety Statements ]
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2929 6.1/PG 2
| [WGK Germany ]
3
| [F ]
9-13-19-21 | [HazardClass ]
3 | [PackingGroup ]
III | [HS Code ]
29309090 |
| Hazard Information | Back Directory | [Hazard]
Lachrymator. | [Chemical Properties]
Light Yellow Oil | [Application]
Ethoxycarbonyl isothiocyanate reacts with 2-amino-tetrahydrobenzo[b]thiophene derivatives to yield tetrahydrobenzo[b]thiophen-2-thiourea derivatives.
Ethoxycarbonyl isothiocyanate has been used in the synthesis of:
pyrazolo[1,5-a][1,3,5]triazine derivatives, potential inhibitors of protein kinase CK2
fused thiophene derivatives, having antibacterial and antifungal activities
4-thiouracil derivatives
thiocarbamides from stannylarenes
1,3,5-triazin-2-one-4-thiones from 2-amino-2-oxazolines
N-acylthioureas from aminodeoxy sugars | [Synthesis Reference(s)]
Using Schiff base as a phase transfer catalyst, ethoxycarbonyl isothiocyanate was synthesized by reacting ethyl chloroformate with sodium thiocyanate. www.semanticscholar.org | [General Description]
Ethoxycarbonyl isothiocyanate reacts with 2-amino-tetrahydrobenzo[b]thiophene derivatives to yield tetrahydrobenzo[b]thiophen-2-thiourea derivatives. |
|
|