| Identification | More | [Name]
2-Trifluoromethylphenylboronic acid | [CAS]
1423-27-4 | [Synonyms]
2-(TRIFLUOROMETHYL)BENZENEBORONIC ACID
2-(TRIFLUOROMETHYL)PHENYLBORONIC ACID
AKOS BRN-0242
ALPHA,ALPHA,ALPHA-TRIFLUORO-O-TOLUENEBORONIC ACID
ALPHA,ALPHA,ALPHA-TRIFLUORO-O-TOLYLBORONIC ACID
O-TRIFLUOROMETHYLPHENYLBORONIC ACID
RARECHEM AH PB 0094
2-Trifluoromethylboronic acid
2-(TRIFLUOROMETHYL)PHENYLBORONIC ACID, 9 7%
2-(Trifluoromethyl)benzeneboronic acid 98%
2-(Trifluoromethyl)benzeneboronicacid98%
2-Boronobenzotrifluoride
2-(Trifluoromethyl)phenylboronic Acid (contains varying amounts of Anhydride)
0-Trufluoromethylboronic Acid
2-(Trifluoromethyl)phenylboronic acid ,98% | [EINECS(EC#)]
640-203-7 | [Molecular Formula]
C7H6BF3O2 | [MDL Number]
MFCD00236059 | [Molecular Weight]
189.93 | [MOL File]
1423-27-4.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light beige crystalline powder | [Melting point ]
111-114 °C (lit.) | [Boiling point ]
274.5±50.0 °C(Predicted) | [density ]
1.36±0.1 g/cm3(Predicted) | [storage temp. ]
0-6°C | [solubility ]
slightly sol. in Methanol | [form ]
powder to crystal | [pka]
8.11±0.58(Predicted) | [color ]
White to Almost white | [Detection Methods]
HPLC,NMR | [BRN ]
2974465 | [InChIKey]
JNSBEPKGFVENFS-UHFFFAOYSA-N | [CAS DataBase Reference]
1423-27-4(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29319099 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light beige crystalline powder | [Uses]
2-(Trifluoromethyl)phenylboronic acid can be used as a reactant:
- In Suzuki-coupling reactions to prepare 2-trifluoromethyl aryl or heteroaryl derivatives.
- To synthesize 4-(2-trifluoromethyl)phenylpyrrolo[2,3-d]pyrimidine as a potential antagonist of corticotropin-releasing hormone.
- To prepare 2-nitro-6-(trifluoromethyl)phenylboronic acid by nitration reaction.
| [Uses]
2-Trifluoromethylphenylboronic Acid is a reagent in the preparation of potent inhibitors of human uric acid transporter 1 (hURAT1). | [Uses]
suzuki reaction |
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