| Identification | More | [Name]
4-Biphenylcarbonyl chloride | [CAS]
14002-51-8 | [Synonyms]
4-BIPHENYLCARBONYL CHLORIDE
4-PHENYLBENZOYL CHLORIDE
BIPHENYL-4-CARBONYL CHLORIDE
P-PHENYLBENZOYL CHLORIDE
[1,1’-biphenyl]-4-carbonylchloride
4-BIPHENYLCARBONYL CHLORIDE CRYSTALLINE
Biphenyl-4-carbonyl chloride 98%
4-Biphenylcarbonyl chloride ,98%
1,1'-Biphenyl-4-carboxylic acid chloride
Biphenyl-4-carboxylic acid chloride | [EINECS(EC#)]
237-804-8 | [Molecular Formula]
C13H9ClO | [MDL Number]
MFCD00000692 | [Molecular Weight]
216.66 | [MOL File]
14002-51-8.mol |
| Chemical Properties | Back Directory | [Appearance]
white to yellow fine crystalline powder | [Melting point ]
110-112 °C (lit.) | [Boiling point ]
160 °C / 2mmHg | [density ]
1.1459 (rough estimate) | [refractive index ]
1.5260 (estimate) | [storage temp. ]
2-8°C
| [form ]
Fine Crystalline Powder | [color ]
White to yellow | [Water Solubility ]
HYDROLYSIS | [Sensitive ]
Moisture Sensitive/Lachrymatory | [Detection Methods]
GC,NMR | [BRN ]
472842 | [InChIKey]
JPVUWCPKMYXOKW-UHFFFAOYSA-N | [CAS DataBase Reference]
14002-51-8(CAS DataBase Reference) | [EPA Substance Registry System]
14002-51-8(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R14:Reacts violently with water.
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S43:In case of fire, use ... (indicate in the space the precise type of fire-fighting equipment. If water increases the risk add-Never use water) .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S25:Avoid contact with eyes . | [RIDADR ]
UN 3261 8/PG 2
| [WGK Germany ]
3
| [F ]
21-10 | [Hazard Note ]
Corrosive/Lachrymatory/Moisture Sensitive | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
29163990 |
| Hazard Information | Back Directory | [Chemical Properties]
4-Biphenylcarbonyl chloride is white to yellow fine crystalline powder
| [Uses]
Biphenyl-4-carbonyl chloride was used in the preparation of a novel thiourea compound, N-(6-methyl pyridin-2-yl-carbamothioyl)biphenyl-4-carboxamide. It was also used in the preparation of 5-CF3-oxazole analog, 2-{4-[2-(2-biphenyl-4-yl-5-trifluoromethyl-oxazol-4-yl)-ethoxy]-phenoxy}-2-methyl-propionic acid.
| [Purification Methods]
Dissolve the carbonyl chloride in a large volume of pet ether (10 x, b 50-70o), filter it through a short column of neutral alumina, evaporate to dryness in vacuo and recrystallise it from pet ether (b 60-80o). [Beilstein 9 IV 2480.] LACHRYMATORY. |
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