| Identification | Back Directory | [Name]
Methyl 4-oxobutanoate | [CAS]
13865-19-5 | [Synonyms]
Einecs 237-611-9
methyl 4-oxobutyrate
Methyl 4-oxobutanoate 90%
4-Oxobutyric acid methyl ester
4-OXOBUTANOIC ACID METHYL ESTER
Succinaldehydic acid, methyl ester
3-Formylpropanoic acid methyl ester
3-Formylpropionic acid methyl ester
Butanoic acid, 4-oxo-, Methyl ester
Methyl 4-oxobutanoate(Methyl 3-ForMylpropionate) | [EINECS(EC#)]
237-611-9 | [Molecular Formula]
C5H8O3 | [MDL Number]
MFCD00082185 | [MOL File]
13865-19-5.mol | [Molecular Weight]
116.12 |
| Chemical Properties | Back Directory | [Boiling point ]
187-188 °C(lit.)
| [density ]
1.109 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.424(lit.)
| [Fp ]
187 °F
| [storage temp. ]
2-8°C | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Oil | [color ]
Colourless | [InChIKey]
DLZVZNAPRCRXEG-UHFFFAOYSA-N | [LogP]
0.110 (est) |
| Questions and Answers (Q&A) | Back Directory | [Description]
Methyl-4-oxobutyrate is a kind of oxobutyrate derivative. It is an
important industrial intermediate. It, together with its methanol
addition products such as methyl 4,4-dimethoxybutyrate and gamma-
methoxy-gamma-butyrolactone are useful intermediates during the
preparation of some important industrial compounds such as gamma-
butyrolactone, 1,4-butanediol and glutamate. It is also useful as a
model substrate during exploring the asymmetric henry reaction since
it can assemble a stereodefined lactam with high efficiency and
enantiomeric purity. | [References]
Gresham, William F, R. E. Brooks, and W. M. Bruner. "Preparation of methyl 4-oxobutyrate." US2549454. 1951.
Murib, Jawad H, and W. D. Baugh. "Process for the preparation of methyl 4-oxobutyrate and its methanol addition products." US, US5072005. 1991.
https://www.scbt.com/scbt/product/methyl-4-oxobutanoate-13865-19-5
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| Hazard Information | Back Directory | [Uses]
Methyl 4-oxobutanoate may be used as a starting material to synthesize (-)-deoxoprosophylline, a piperidine alkaloid with therapeutic potential. |
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