| Identification | More | [Name]
2-Cyanophenylboronic acid | [CAS]
138642-62-3 | [Synonyms]
2-CYANOBENZENEBORONIC ACID
2-CYANOPHENYLBORONIC ACID
AKOS BRN-0034
RARECHEM AH PB 0208
2-Boronobenzonitrile
Boronic acid, (2-cyanophenyl)-(9CI)
2-Cyanophenylboronic acid, >90%
o-CyanophenylboronicAcid | [EINECS(EC#)]
604-090-8 | [Molecular Formula]
C7H6BNO2 | [MDL Number]
MFCD01632208 | [Molecular Weight]
146.94 | [MOL File]
138642-62-3.mol |
| Chemical Properties | Back Directory | [Appearance]
off-white to cream powder | [Melting point ]
240 °C (dec.) (lit.) | [Boiling point ]
376.4±44.0 °C(Predicted) | [density ]
1.25±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
Soluble in methanol. | [form ]
Powder | [pka]
7.98±0.58(Predicted) | [color ]
Off-white to cream | [Detection Methods]
HPLC | [InChIKey]
NPLZNDDFVCGRAG-UHFFFAOYSA-N | [CAS DataBase Reference]
138642-62-3(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S37/39:Wear suitable gloves and eye/face protection .
S36:Wear suitable protective clothing . | [RIDADR ]
3439 | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HS Code ]
29319099 |
| Hazard Information | Back Directory | [Chemical Properties]
off-white to cream powder | [Uses]
2-Cyanophenylboronic Acid is used in the synthesis of pyridine inhibitors of TAK1. Also participates in the discovery and synthesis of 1,2,4-triazoles as novel allosteric valosine containing protein (VCP) inhibitors. VCP is found highly abundant in various tumor types allowing for a potential target in cancer therapy. |
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