| Identification | More | [Name]
Benz[cd]indol-2(1H)-one | [CAS]
130-00-7 | [Synonyms]
1,2-DIHYDROBENZO[CD]INDOL-2-ONE
1,8-NAPHTHOLACTAM
BENZ[CD]INDOL-2(1H)-ONE
BENZO[CD]INDOL-2(1H)-ONE
NAPHTHOSTYRIL
2(1h)-perinaphthazolone
naphtholactam
1,8-Naphthaolactam
Naphthostyril 1,8-Naphtholactam
1,8-Naphthostyril
2H-benzo[f]indol-2-one
benz(cd)indol-2(1H)-one/1,8-Naphthaolactam /Naphthostyril
BENZ(CD)INDOL-2(1H)-ONE, TECH.
NAPHTHOSTYRIL+98%
1,8-Naphtholactame
1H-BENZO[CD]INDOL-2-ONE
Benz(cd)indol-2(1H)-on
8-Amino-1-naphtholactam
NAPHTHOLAS-G
1,8-Naphthaleneformylimine | [EINECS(EC#)]
204-973-4 | [Molecular Formula]
C11H7NO | [MDL Number]
MFCD00009748 | [Molecular Weight]
169.18 | [MOL File]
130-00-7.mol |
| Chemical Properties | Back Directory | [Melting point ]
173-178 °C(lit.)
| [Boiling point ]
298.46°C (rough estimate) | [density ]
1.1616 (rough estimate) | [vapor pressure ]
0.61-7.2Pa at 100-130℃ | [refractive index ]
1.4900 (estimate) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
methanol: soluble25mg/mL, clear to slightly hazy, yellow to brown | [form ]
Powder | [pka]
13.27±0.20(Predicted) | [color ]
Light orange to Yellow to Green | [InChI]
InChI=1S/C11H7NO/c13-11-8-5-1-3-7-4-2-6-9(12-11)10(7)8/h1-6H,(H,12,13) | [InChIKey]
GPYLCFQEKPUWLD-UHFFFAOYSA-N | [SMILES]
N1C2=C3C(C=CC=C3C1=O)=CC=C2 | [LogP]
2.5 at 24℃ and pH6.6 | [CAS DataBase Reference]
130-00-7(CAS DataBase Reference) | [EPA Substance Registry System]
130-00-7(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed. | [Safety Statements ]
24/25 | [WGK Germany ]
2
| [RTECS ]
DE3202000
| [HS Code ]
29337900 | [Toxicity]
mammal (species unspecified),LD50,oral,2700mg/kg (2700mg/kg),BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY),Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 51(1), Pg. 82, 1986. |
| Hazard Information | Back Directory | [Uses]
• ;Reactant in photo-Fries rearrangement1• ;Reactant in preparation of potential antitumor agents2• ;Reactant in synthesis of inhibitors of thymidylate synthase3 | [Uses]
Benz[cd]indol-2(1H)-one was used in the synthesis of 2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide analog, novel Mycobacterium protein tyrosine phosphatase B (mPTPB) inhibitor. | [General Description]
Benz[cd]indol-2(1H)-one is also referred as naphtholactam. |
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