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ChemicalBook--->CAS DataBase List--->125926-17-2

125926-17-2

125926-17-2 Structure

125926-17-2 Structure
IdentificationBack Directory
[Name]

Sarpogrelate
[CAS]

125926-17-2
[Synonyms]

Sapogrelate
SARPOGRELATE
Sarpogrelate USP/EP/BP
(+/-)-2-(dimethylamino)-1-{(o-(m-methoxyphenethyl)phenoxy)methyl}ethyl hydrogen succinate
4-[1-(dimethylaminomethyl)-2-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]ethoxy]-4-keto-butyric acid
4-[1-(dimethylamino)-3-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]propan-2-yl]oxy-4-oxobutanoic acid
4-[1-(dimethylamino)-3-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]propan-2-yl]oxy-4-oxo-butanoic acid
Butanedioic acid, 1-[2-(diMethylaMino)-1-[[2-[2-(3-Methoxyphenyl)ethyl]phenoxy]Methyl]ethyl] ester
Butanedioic acid, mono[2-(dimethylamino)-1-[[2-[2-(3-methoxyphenyl)ethyl]phenoxy]methyl]ethyl] ester (9CI)
[Molecular Formula]

C24H31NO6
[MDL Number]

MFCD00866779
[MOL File]

125926-17-2.mol
[Molecular Weight]

429.51
Chemical PropertiesBack Directory
[Boiling point ]

585.9±50.0 °C(Predicted)
[density ]

1.164±0.06 g/cm3(Predicted)
[pka]

4.25±0.17(Predicted)
Hazard InformationBack Directory
[Uses]

Sarpogrelate (MCI-9042) is a new, specific orally active 5-HT2 receptor antagonist, Sarpogrelate increases platelet aggregation and has hemostasis effect, and can be used for the research of Buerger’s disease[1].
[Definition]

ChEBI: Sarpogrelate is a stilbenoid and a hemisuccinate.
[IC 50]

5-HT2 Receptor
[References]

[1] A Rydzewski, et al. The effect of a 5HT2 receptor antagonist sarpogrelate (MCI-9042) treatment on platelet function in Buerger's disease. Thromb Res. 1996 Dec 15;84(6):445-52. DOI:10.1016/s0049-3848(96)00212-5
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