| Identification | Back Directory | [Name]
isoliquiritin apioside | [CAS]
120926-46-7 | [Synonyms]
Neolicuroside
isoliquiritin apioside
(2E)-3-[4-[(2-O-D-apio-beta-D-furanosyl-beta-D-glucopyranosyl)oxy]phenyl]-1-(2,4-dihydroxyphenyl)-2-propen-1-one | [Molecular Formula]
C26H30O13 | [MDL Number]
MFCD20487832 | [MOL File]
120926-46-7.mol | [Molecular Weight]
550.51 |
| Chemical Properties | Back Directory | [Boiling point ]
901.0±65.0 °C(Predicted) | [density ]
1.63 | [storage temp. ]
-20°C, protect from light | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
7.46±0.35(Predicted) | [color ]
Yellow to orange | [biological source]
plant | [Water Solubility ]
water: slightly soluble | [CAS DataBase Reference]
120926-46-7 |
| Hazard Information | Back Directory | [Chemical Properties]
White powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from licorice. | [Uses]
Isoliquiritin apioside can be used to resist myocardial ischemia and inhibit the proliferation of HIV. | [Definition]
ChEBI:Neolicuroside is a member of flavonoids and a glycoside. | [Biological Activity]
Neolicuroside modulates signaling pathways (e.g.MAPKNF-KB)impacting vital cell processes such as proliferationdifferentiationand apoptosis. Its multitargeted mechanism includes scavenging free radicalssuppressing pro-inflammatory cytokine productioninhibiting matrix metalloproteinase (MMP) activity and hindering cancer cell growth through apoptosis and cell cycle arrest. Furthermoreit also exerts immunomodulatory effects possibly by activating toll-like receptor 4 (TLR4). | [storage]
-20°C, protect from light |
|
|