| Identification | More | [Name]
4-Aminothiophenol | [CAS]
1193-02-8 | [Synonyms]
4-AMINOBENZENETHIOL
4-AMINOPHENYL MERCAPTAN
4-AMINOTHIOPHENOL
4-MERCAPTOANILINE
BENZENETHIOL, 4-AMINO-
LABOTEST-BB LTBB000715
P-AMINOBENZENETHIOL
P-AMINOPHENYL MERCAPTAN
P-AMINOTHIOPHENOL
4-amino-benzenethio
Benzenethiol, p-amino-
p-amino-benzenethio
p-Mercaptoaniline
4-Aminobenzenethiol~4-Mercaptoaniline
4-Aminothiophenol, (4-Aminobenzenethiol
4-Aminothiophenol/4-Aminobenzenethiol
4-Aminothophenol
4-Aminothiophenol
4-Aminobenzenethiol
4-Mercaptoaniline
4-Mercaptoaniline
4-Aminobenzenethiol
4-AMINOTHIOPHENOL, ~90-95%
4-Aminobenzenethiol, 4-Aminophenyl mercaptan, 4-Mercaptoaniline | [EINECS(EC#)]
214-763-4 | [Molecular Formula]
C6H7NS | [MDL Number]
MFCD00007880 | [Molecular Weight]
125.19 | [MOL File]
1193-02-8.mol |
| Chemical Properties | Back Directory | [Appearance]
yellow crystalline low melting mass | [Melting point ]
37-42 °C(lit.) | [Boiling point ]
140-145 °C16 mm Hg(lit.) | [density ]
1.136 (estimate) | [refractive index ]
1.4606 (estimate) | [Fp ]
>230 °F
| [storage temp. ]
2-8°C
| [solubility ]
7.3g/l | [form ]
Crystals, Flakes or Crystalline Mass | [pka]
8.74±0.10(Predicted) | [color ]
Off-white to brown | [Water Solubility ]
Immiscible with water. | [Sensitive ]
Stench | [BRN ]
906904 | [CAS DataBase Reference]
1193-02-8(CAS DataBase Reference) | [NIST Chemistry Reference]
4-Aminothiophenol(1193-02-8) | [Storage Precautions]
Air sensitive | [EPA Substance Registry System]
1193-02-8(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns.
R37:Irritating to the respiratory system. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S25:Avoid contact with eyes .
S27:Take off immediately all contaminated clothing . | [RIDADR ]
UN 3263 8/PG 2
| [WGK Germany ]
3
| [RTECS ]
DC0602500
| [F ]
10-13-23 | [Hazard Note ]
Corrosive/Stench | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29309070 |
| Hazard Information | Back Directory | [Chemical Properties]
yellow crystalline low melting mass | [Uses]
4-Aminothiophenol (4-ATP) was employed as bifunctional molecule to functionalize gold nanoparticles (NPs) used in surface-enhanced Raman spectroscopy (SERS) detection of thrombin by protein recognition.
| [Uses]
4-Aminothiophenol is used in the synthesis of pectin-4-aminothiophenol conjugates and it forms self-assembled monolayers (SAMs) in the development of DNA. It is used in the detection of thrombin by protein recognition using surface-enhanced Raman spectroscopy (SERS), which finds applications in silver and gold nano particles. It acts as a linker to thiol (SH) functionalizes multiwalled carbon nanotubes (MWCNTs). | [Preparation]
synthesis of 4-aminothiophenol: A mixture of 128 g. of p-chloronitrobenzene and a solution of 480 g. of sodium sulfide nonahydrate in 2 l. of water is heated to reflux for 8 hours. The cooled mixture is extracted with ether to remove a small amount of oil, the remaining aqueous solution is saturated with sodium chloride, and 240 g. of glacial acetic acid is added. The precipitated oil is removed by ether extraction, and the resulting ethereal solution is dried over sodium sulfate and distilled to give 70 g. (69%) of 4-aminothiophenol boiling at 143-146°/17 mm. and melting at 43-45°. | [General Description]
4-Aminothiophenol (p-aminothiophenol, PATP) is an aromatic thiol. The self-assembly of silver and gold nano particles which are interconnected with 4-ATP to form metal-molecule-metal sandwich architecture has been characterized by surface enhanced Raman scattering (SERS) using an off-surface plasmon resonance condition. Chemical transformation of PATP to 4,4-dimercaptoazobenzene (DMAB) has been extensively studied. |
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