869718-81-0

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869718-81-0 Structure

Identification	Back Directory
[Name] 3,6,9,12,15,18,21,24-Octaoxapentacosan-1-amine
[CAS] 869718-81-0
[Synonyms] MPEG8-NH2 m-PEG8-amine m-dPEG8-Amine m-dPEG??-amine m-dPEG(R)8-amine 3,6,9,12,15,18,21,24- 3,6,9,12,15,18,21,24-Octaoxapentacosan-1-amine 2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
[Molecular Formula] C17H37NO8
[MDL Number] MFCD13184961
[MOL File] 869718-81-0.mol
[Molecular Weight] 383.48

Chemical Properties	Back Directory
[Boiling point ] 448.0±40.0 °C(Predicted)
[density ] 1.054
[storage temp. ] -20°C
[solubility ] Soluble in Water
[form ] solid or viscous liquid
[pka] 8.74±0.10(Predicted)
[color ] Colorless to light yellow

Safety Data	Back Directory
[Symbol(GHS) ] GHS07
[Signal word ] Warning
[Hazard statements ] H315-H319
[Precautionary statements ] P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
[HS Code ] 2922190090

Hazard Information

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[Description]

m-PEG8-amine is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases solubility in aqueous media.

[reaction suitability]

reagent type: chemical modification reagent
reagent type: cross-linking reagent
reactivity: carboxyl reactive

[Biological Activity]

m-PEG8-Amine is a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs).

[target]

Cleavable

PEGs

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