| Identification | Back Directory | [Name]
XL-388 | [CAS]
1251156-08-7 | [Synonyms]
XL388
XL-388
XL 388
CS-772
XL388, >=98%
XL-388;XL 388
XL-388 USP/EP/BP
Carbamazepine 298-46-4 three units, HPLC Purity : XL388
(7-(6-Aminopyridin-3-yl)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)(3-fluoro-2-methyl-4-(methy
[7-(6-Amino-3-pyridinyl)-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl][3-fluoro-2-methyl-4-(methylsulfonyl)phenyl]-methanone
Methanone, [7-(6-amino-3-pyridinyl)-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl][3-fluoro-2-methyl-4-(methylsulfonyl)phenyl]-
[7-(6-Amino-3-pyridinyl)-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl][3-fluoro-2-methyl-4-(methylsulfonyl)phenyl]-methanone XL388 | [Molecular Formula]
C23H22FN3O4S | [MDL Number]
MFCD24386875 | [MOL File]
1251156-08-7.mol | [Molecular Weight]
455.5 |
| Chemical Properties | Back Directory | [Melting point ]
>188oC (dec.) | [Boiling point ]
738.6±60.0 °C(Predicted) | [density ]
1.354±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
6.22±0.13(Predicted) | [color ]
Off-White to Pale Yellow | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
XL388 is a highly potent, orally bioavailable, selective, ATP-competitive mammalian target of rapamycin (mTOR) inhibitor. XL388 has shown significant and dose-dependent antitumor activity in athymic nude mice implanted with human tumor xenografts. | [storage]
Store at -20°C |
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