| Identification | More | [Name]
2-Pyridinethiol 1-oxide | [CAS]
1121-31-9 | [Synonyms]
1-HYDROXY-2(1H)-PYRIDINETHIONE
1-HYDROXY-2-PYRIDINETHIONE
2-MERCAPTOPYRIDINE-1-OXIDE
2-MERCAPTOPYRIDINE N-OXIDE
2-MERCAPTYPYRIDINE-N-OXIDE
2-PYRIDINETHIOL 1-OXIDE
N-HYDROXY-2-PYRIDINE THIONE
PYRIDINE-2-THIOL-1-OXIDE
PYRITHIONE
1-Oxido-2-pyridinyl hydrosulfide
2-Mercaptopyridine monoxide
2-mercaptopyridinemonoxide
Omadine
1-Hydroxypyridine-2-thione
2-Mercaptypyridine-N-oxide anhydrous
2-Pyridinethiol N-oxide
MercaptopyridineNoxide
MercaptypyridineNoxideanhydrous
N-Hydroxy-2-thiopyridone
pyridine-2-thiol N-oxide | [EINECS(EC#)]
214-329-4 | [Molecular Formula]
C5H5NOS | [MDL Number]
MFCD00006196 | [Molecular Weight]
127.16 | [MOL File]
1121-31-9.mol |
| Chemical Properties | Back Directory | [Appearance]
off-white powder | [Melting point ]
69-72 °C (lit.) | [Boiling point ]
350.2±15.0 °C(Predicted) | [density ]
1.255 (estimate) | [refractive index ]
1.5480 (estimate) | [storage temp. ]
Refrigerator | [solubility ]
Soluble in tris-hydrochloric acid. | [form ]
Powder, Crystals, and/or Chunks | [pka]
5.40±0.50(Predicted) | [color ]
Off-white to beige or yellow to yellow-greenish or grayish-green | [Stability:]
Stable. Incompatible with strong bases, strong oxidizing agents. | [Sensitive ]
Air & Light Sensitive | [Merck ]
14,7994 | [BRN ]
906983 | [CAS DataBase Reference]
1121-31-9(CAS DataBase Reference) | [NIST Chemistry Reference]
2-Mercaptopyridine-n-oxide(1121-31-9) | [EPA Substance Registry System]
1121-31-9(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R22:Harmful if swallowed.
R63:Possible risk of harm to the unborn child.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S24/25:Avoid contact with skin and eyes .
S36/37:Wear suitable protective clothing and gloves .
S22:Do not breathe dust . | [RIDADR ]
2811 | [WGK Germany ]
3
| [RTECS ]
UT8999000
| [F ]
8-10-13-23 | [TSCA ]
Yes | [HS Code ]
29333990 |
| Hazard Information | Back Directory | [Chemical Properties]
off-white powder | [Uses]
2-Mercaptopyridine N-oxide is used in ratiometric fluorescence imaging of intracellular zinc ions in mammalian cultures. It is used in the radical coupling of benzoyl derivatives of 2-deoxy-D-ribose, with heterocyclic bases to give C-nucleosides. It acts as a ligand and form coordination complexes with palladium chloride. It is a precursor to O-acyl thiohydroxamates. Further, it serves as an antifungal agent. In addition to this, it is used in the preparation of 1-oxa-2-oxo-3-thia-indolizinium chloride by reaction with carbonyl dichloride. | [Definition]
ChEBI:Pyrithione is a pyridinethione that is pyridine-2(1H)-thione in which the hydrogen attached to the nitrogen is replaced by a hydroxy group. It is a Zn(2+) ionophore; the zinc salt is used as an antifungal and antibacterial agent. It has a role as an ionophore. It is a pyridinethione and a monohydroxypyridine. It is a tautomer of a pyridine-2-thiol N-oxide. | [General Description]
2-Mercaptopyridine N-oxide forms complexes on reaction with palladium chloride. It inhibits NADH-fumarate reductase purified from Trypanosoma cruzi. It is precursor to O-acyl thiohydroxamates. It ligates to metals to form biologically active complexes. |
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