| Identification | More | [Name]
Sodium thioglycolate | [CAS]
367-51-1 | [Synonyms]
MERCAPTOACETIC ACID SODIUM SALT
NATG
SODIUM MERCAPTOACETATE
SODIUM THIOGLYCOLATE
SODIUM THIOGLYCOLLATE
THIOGLYCOLIC ACID SODIUM SALT
Aceticacid,mercapto-,monosodiumsalt
Mercaptoaceticacidmonosodiumsalt
mercapto-aceticacimonosodiumsalt
thioglycolatedesodium
thioglycolatesodium
thioglycollicacid,sodiumsalt
usafek-5199
Sodium thiobycliate
SODIUM THIOGLYKOLATE
SODIUME THINOBYCLIATE
SodiumThioglycollate,>96%
SodiumThioglycollateForBacteriology
SODIUM THIOGLYCOLATE (FOR BACTERIOLOGY)
Mercaptoaceticacidsodiumsalt,97% | [EINECS(EC#)]
206-696-4 | [Molecular Formula]
C2H3NaO2S | [MDL Number]
MFCD00043386 | [Molecular Weight]
114.1 | [MOL File]
367-51-1.mol |
| Chemical Properties | Back Directory | [Definition]
The sodium salt of thioglycolic acid.
| [Appearance]
White solid | [Melting point ]
>300 °C (lit.) | [vapor pressure ]
<0.1 hPa (25 °C) | [storage temp. ]
2-8°C
| [solubility ]
609.1g/l | [form ]
solid | [pka]
3.82[at 20 ℃] | [color ]
White powder | [Odor]
Stench odour | [PH]
6.7 (100g/l, H2O, 20℃) | [PH Range]
6.5 - 8 at 114 g/l at 25 °C | [Water Solubility ]
soluble | [Sensitive ]
Air Sensitive & Hygroscopic | [Merck ]
14,8692 | [BRN ]
4569109 | [Exposure limits]
ACGIH: TWA 1 ppm (Skin) | [LogP]
-2.99 at 20℃ | [CAS DataBase Reference]
367-51-1(CAS DataBase Reference) | [EPA Substance Registry System]
367-51-1(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed.
R38:Irritating to the skin.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S36:Wear suitable protective clothing .
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
2811 | [WGK Germany ]
1
| [RTECS ]
AI7700000
| [F ]
3-10-13-23 | [TSCA ]
Yes | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [HS Code ]
29309070 | [Safety Profile]
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. A human skin irritant. This material yields hydrogen sulfide on decomposition. A death has been attributed to the absorption of toxic decomposition products from the use of this material in a hair permanent-waving solution. When heated to decomposition it emits toxic fumes of SOx and Na2O. See also SULFIDES and MERCAPTANS. | [Toxicity]
LD50 i.p. in rats: 148 mg/kg, Freeman, Rosenthal, Fed. Proc. 11, 347 (1952) |
| Hazard Information | Back Directory | [General Description]
White powder with a slight odor. Used in cold-waving of hair and as a dipilatory. | [Reactivity Profile]
THIOGLYCOLIC ACID, SODIUM SALT(367-51-1) is hygroscopic and sensitive to air. Discolors if exposed to iron . May generate flammable and toxic hydrogen sulfide with strong reducing agents. | [Air & Water Reactions]
Hygroscopic. Discolors on exposure to air. Water soluble. | [Hazard]
Yields toxic hydrogen sulfide on decompo-
sition, may be toxic by skin absorption.
| [Fire Hazard]
Flash point data for this chemical are not available. THIOGLYCOLIC ACID, SODIUM SALT is probably combustible. | [Chemical Properties]
White solid | [Uses]
dipilatory, irritant, chelating agent | [Uses]
In cold-waving of hair; as depilatory; in bacteriology for the preparation of thioglycolate media; as analytical reagent, see Thioglycolic Acid. | [Flammability and Explosibility]
Nonflammable | [Biochem/physiol Actions]
Sodium thioglycolate is a commonly used reagent for bacteriological research to maintain reducing conditions in media. Thioglycolate can also protect enzymes against inactivation by maintaining protein thiol groups in the reduced state. Thioglycolate medium is frequently used in inflammation research to elicit a neutrophil and macrophage response in vivo. | [Purification Methods]
It crystallises from 60% EtOH (charcoal). It is hygroscopic.[Beilstein 3 IV 600.] |
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