| Identification | More | [Name]
Diethyl carbonate | [CAS]
105-58-8 | [Synonyms]
2-CHLORO ETHYL DIETHYL AMINE HCL
(2-CHLORO-ETHYL)-DIETHYL-AMINE HYDROCHLORIDE
2-CHLORO-N,N-DIETHYLAMINE HYDROCHLORIDE
2 CHLORO-N,N-DIETHYLETHANAMINE HYDROCHLORIDE
2-chloro-n,n-diethylethaneamine hydrochloride
2-CHLORO-N,N-DIETHYLETHYLAMINE HYDROCHLORIDE
2-CHLOROTRIETHYLAMINE HYDROCHLORIDE
2-DIETHYLAMINO ETHYLCHLORIDE HCL
2-DIETHYLAMINOETHYL CHLORIDE HYDROCHLORIDE
B-CHLOROETHYLDIETHYLAMINE HYDROCHLORIDE
BETA-CHLOROETHYLDIETHYLAMINE HCL
BETA-DIETHYLAMINOETHYLCHLORIDE HYDROCHLORIDE
CARBONIC ACID DIETHYL ESTER
CARBONIC ACID DIETHYL ESTHER
carbonic ether
CED
DEC
DIETHYLAMINO ETHYL CHLORIDE HCL
DIETHYLAMINOETHYLCHLORIDE HYDROCHLORIDE
DIETHYL CARBONATE | [EINECS(EC#)]
212-786-4 | [Molecular Formula]
C5H10O3 | [MDL Number]
MFCD00009107 | [Molecular Weight]
118.13 | [MOL File]
105-58-8.mol |
| Chemical Properties | Back Directory | [Appearance]
colourless liquid with a mild odour | [Melting point ]
-43 °C (lit.) | [Boiling point ]
126-128 °C (lit.) | [density ]
0.975 g/mL at 25 °C(lit.)
| [vapor density ]
4.1 (vs air)
| [vapor pressure ]
10 mm Hg ( 23.8 °C)
| [refractive index ]
n20/D 1.384(lit.)
| [Fp ]
88 °F
| [storage temp. ]
Flammables area | [solubility ]
18.8mg/l insoluble | [form ]
Liquid | [color ]
Clear | [Odor]
Pleasant, etheral; mild and nonresidual. | [PH]
6.3 (1g/l, H2O) | [Stability:]
Stable. Flammable. Incompatible with strong acids, strong bases, reducing agents, oxidizing agents. Protect from moisture. | [explosive limit]
1.4-11.0%(V) | [Water Solubility ]
Negligible | [Sensitive ]
Moisture Sensitive | [Merck ]
14,3780 | [BRN ]
956591 | [Dielectric constant]
2.8（Ambient） | [LogP]
1.21 at 25℃ | [CAS DataBase Reference]
105-58-8(CAS DataBase Reference) | [NIST Chemistry Reference]
Carbonic acid, diethyl ester(105-58-8) | [EPA Substance Registry System]
105-58-8(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
T,Xi | [Risk Statements ]
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin .
R10:Flammable. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S16:Keep away from sources of ignition-No smoking .
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) . | [RIDADR ]
UN 2811 6.1/PG 2 | [WGK Germany ]
3 | [RTECS ]
YE1050000 | [F ]
21 | [Autoignition Temperature]
445 °C | [TSCA ]
Yes | [HazardClass ]
3 | [PackingGroup ]
III | [HS Code ]
2920 90 10 | [Safety Profile]
Wdly toxic by
subcutaneous route. Questionable
carcinogen with experimental tumorigenic
and teratogenic data. A dangerous fire
hazard when exposed to heat or flame; can
react with oxidizing materials. To fight fire,
use foam, CO2, dry chemical. When heated
to decomposition it emits acrid smoke and
fumes. See also ANHYDRIDES. | [Hazardous Substances Data]
105-58-8(Hazardous Substances Data) | [Toxicity]
LD50 orally in Rabbit: > 4900 mg/kg
LC50 (inhalation) > 21 mg/kg (mouse)
TDL0 500 mg/kg (mouse)
LD50 (s.c.) 8500 mg/kg (rat) |
| Hazard Information | Back Directory | [General Description]
A colorless liquid with a mild pleasant odor. DIETHYL CARBONATE(105-58-8) is slightly less dense than water and insoluble in water. Hence floats on water. Flash point 77°F. Vapors are heavier than air. When heated to high temperatures DIETHYL CARBONATE(105-58-8) may emit acrid smoke. Used as a solvent. | [Reactivity Profile]
DIETHYL CARBONATE reacts with acids to liberate heat along with ethanol and carbon dioxide. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction with caustic solutions. Flammable hydrogen is generated by mixing with alkali metals and hydrides. | [Air & Water Reactions]
Highly flammable. Insoluble in water. | [Health Hazard]
High vapor concentrations can cause headache, irritation of eyes and respiratory tract, dizziness, nausea, weakness, loss of consciousness. | [Chemical Properties]
colourless liquid with a mild odour | [Uses]
Diethyl carbonate is esters, beta-enamino esters, carbamates and unsymmetrical alkyl carbonates. It is an active component of electrolytes used in lithium which is used as a solvent for cellulose ethers, nitro cellulose, natural and synthetic resin and in erythromycin intramuscular injections. It is also used in the synthesis of 3-ethyl-4-methyl-5-phenyl-3H-oxazol-2-one, phenobarbital, pyrethrum batteries. | [Uses]
Solvent for nitrocellulose; manufacture of radio tubes; fixing rare earths to cathode elements. | [Application]
Diethyl carbonate is a well-known linear organic carbonate that has wide applications. It is an active component of electrolytes used in lithium which is used as a solvent for cellulose ethers, nitro cellulose, manufacture of radio tubes, fixing rare earths to cathode elements, natural and synthetic resin and in erythromycin intramuscular injections. It is also used in the synthesis of 3-ethyl-4-methyl-5-phenyl-3H-oxazol-2-one, phenobarbital, pyrethrum batteries. | [Definition]
ChEBI: Diethyl carbonate is a carbonate ester. | [Preparation]
Diethyl carbonate is prepared by reaction of phosgene and ethyl alcohol to produce ethyl chlorocarbonate followed by reaction with anhydrous ethylalcohol at elevated temperatures. direct synthesis of diethyl carbonate (dec) by carboxylation of ethanol with co2 was investigated over ceria catalysts. | [Production Methods]
Manufacturing steps: (a) reacting chlorine and carbon monoxide
to produce (COCl2); (b) reacting phosgene with ethyl
alcohol to make ethyl chlorocarbonate (ClCO2C2H5);
(c) reacting ethyl chlorocarbonate with anhydrous ethyl
alcohol to produce diethyl carbonate. | [Synthesis Reference(s)]
Journal of the American Chemical Society, 104, p. 1769, 1982 DOI: 10.1021/ja00370a068 | [Flammability and Explosibility]
Flammable | [Chemical Reactivity]
Reactivity with Water Too slow to be hazardous; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent. | [Carcinogenicity]
A study using male and female
mice treated with 0, 50, 250, or 1000 ppm (0–140 mg/kg/day)
diethyl carbonate in drinking water indicated no carcinogenic
effects. | [Purification Methods]
Wash the ester (100mL) with an aqueous 10% Na2CO3 (20mL) solution, saturated CaCl2 (20mL), then water (30mL). After drying by standing over solid CaCl2 for 1hour (note that prolonged contact should be avoided because slow combination with CaCl2 occurs), it should be fractionally distilled. Also dry it over MgSO4 and distil it. [Beilstein 3 H 5, 3 I 4, 3 II 4, 3 III 5, 3 IV 5.] |
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