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ChemicalBook--->CAS DataBase List--->1028206-56-5

1028206-56-5

1028206-56-5 Structure

1028206-56-5 Structure
IdentificationBack Directory
[Name]

XPhos Pd G1
[CAS]

1028206-56-5
[Synonyms]

XPhos Pd
XPhos Pd G1
XPhos precatalyst
XPhos Palladacycle
[2-(2-AMinoethyl)phenyl](chloro)palladiuM-dicyclohexyl(2',4',6'-triisopropyl-2-biphenylyl)phosphine (1:1)
Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II)
Chloro(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2-aminoethyl)phenyl)]palladium(II)
Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct
Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aMinoethyl)phenyl]palladiuM(II)Methyl-t-butyletheradduct,Min.98%
Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct, min. 98%
Palladium, [2-[2-(amino-KappaN)ethyl]phenyl-KappaC]chloro[dicyclohexyl[2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine]-, (SP-4-4)-
Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aMinoethyl)phenyl] palladiuM(II) Methyl-t-butylether adduct,98% XPhos Palladacycle
Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct, min. 98% [XPhos Palladacycle]
Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct, min. 98% [XPhos Palladacycle Gen. 1]
[EINECS(EC#)]

1592732-453-0
[Molecular Formula]

C41H59ClNPPd
[MDL Number]

MFCD13194128
[MOL File]

1028206-56-5.mol
[Molecular Weight]

738.77
Chemical PropertiesBack Directory
[Melting point ]

205-210°C
[form ]

Powder
[color ]

white
[CAS DataBase Reference]

1028206-56-5
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38-52/53
[Safety Statements ]

26-61
[WGK Germany ]

3
[HS Code ]

2843909000
Questions And AnswerBack Directory
[Reaction]

  1. Catalyst for cross-coupling reactions of electron-deficient anilines with aryl chlorides.
  2. Catalyst for rapid C-N bond-forming process at low catalyst loading.
  3. Catalyst for C-N cross-coupling reactions, at or below room temperature.
  4. Catalyst for the synthesis of tetracyclic indoles via intermolecular α-arylation of ketones.
  5. Catalyst for the cross-coupling of benzyl chlorides with cyclopropanol-derived ketone homoenolates
Reactions of 1028206-56-5_1
Reactions of 1028206-56-5_2
Reactions of 1028206-56-5_3
Hazard InformationBack Directory
[Uses]

XPhos Pd G1 is used as androgen receptor modulator for treatment of disorders including prostate cancer.
[Preparation]

XPhos Pd G1 is an insoluble solid that can be prepared by cross-coupling reactions of imidazole derivatives with dioxane. 
[General Description]

Material may contain up to 5% pentane
[Physiological effects]

XPhos Pd G1 has been shown to have anti-infectious properties against bacteria and viruses including influenza A, respiratory syncytial virus (RSV), human immunodeficiency virus (HIV), and hepatitis B. It also has metabolic effects on the body by reducing levels of pyridine compounds and increasing pyrazolyl concentrations in the blood stream. 
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