YUIHJWVNGQTMNF-GQCTYLIASA-N synthesis
3synthesis methods
- Product Name:YUIHJWVNGQTMNF-GQCTYLIASA-N
- CAS Number:852181-14-7
- Molecular formula:C11H11FO3
- Molecular Weight:210.2
Yield:852181-14-7 75%
Reaction Conditions:
Stage #1: Methyl diethylphosphonoacetatewith sodium hydride in N,N-dimethyl-formamide at 0 - 20; for 0.583333 h;
Stage #2: 2-fluoro-4-methoxy-benzaldehyde in N,N-dimethyl-formamide at 20; for 20 h;Horner-Emmons reaction;
References:
Parsons, Jack G.;Stachurska-Buczek, Danuta;Choi, Neil;Griffiths, Peter G.;Huggins, Daniel A.;Krywult, Beata M.;Marino, Sharon T.;Nguyen, Thao;Sheehan, Craig S.;James, Ian W.;Bray, Andrew M.;White, Jonathan M.;Boyce, Rustum S. [Molecules,2004,vol. 9,# 6,p. 449 - 458]
