Velpatasvir-A12 synthesis
- Product Name:Velpatasvir-A12
- CAS Number:1377604-63-1
- Molecular formula:C49H56N8O8
- Molecular Weight:885.02
1378391-43-5
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Yield:-
Steps:
Multi-step reaction with 3 steps
1: ammonium acetate / toluene; 2-methoxy-ethanol / 4.5 h / 110 °C
2: hydrogenchloride / dichloromethane; 1,4-dioxane / 0.5 h / 20 °C
3: N-ethyl-N,N-diisopropylamine; 1-[(1-(cyano-?2-?ethoxy-?2-?oxoethylidenaminooxy)?dimethylamino-?morpholino)]-uronium hexafluorophosphate / N,N-dimethyl-formamide / 0.33 h / 20 °C
References:
WO2013/75029,2013,A1
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1378391-39-9
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1377604-63-1
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1378391-42-4
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487048-28-2
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$12.00/250mg
1377604-63-1
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