ChemicalBook CAS DataBase List TRANS-BETA-NITROSTYRENE

TRANS-BETA-NITROSTYRENE synthesis

10synthesis methods

Product Name:TRANS-BETA-NITROSTYRENE
CAS Number:102-96-5
Molecular formula:C8H7NO2
Molecular Weight:149.15

621-82-9 Synthesis

621-82-9
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Yield:102-96-5 72%

Reaction Conditions:

with trichloroisocyanuric acid;N,N-dimethyl-formamide;sodium nitrite for 8 h;Reflux;

Steps:

Conventional Procedure for Synthesis of Nitro Compounds Using TCICA/DMF Reagent
General procedure: To 0.01 mol phenol (as a typical example for aromatic compounds), about 0.01 mol of TCICA/DMF reagent and sodium nitrite (1g) were added with CH2Cl2 or acetonitrile (25mL) in a previously cleaned round-bottom flask and stirred under reflux condition about 8 to 10 h. The completion of there action was checked by TLC. After completion there action mixture was washed with NaHCO3 solution and then treated with ethylacetate. The organic layer was separated, dried over anhydrous MgSO4, evaporated under vacuum, and purified with column chromatography using ethylacetate-hexane as eluent to get pure product 4-nitrophenol as yellow powder

References:

Kumar, Mukka Satish;Rajanna, Kamatala Chinna;Venkateswarlu, Marri;Venkanna, Purugula;Saiprakash, Pondichery Kuppuswamy [Synthetic Communications,2015,vol. 45,# 19,p. 2251 - 2258]

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