tert-Butyl N-cyclohexylcarbaMate synthesis
- Product Name:tert-Butyl N-cyclohexylcarbaMate
- CAS Number:3712-40-1
- Molecular formula:C11H21NO2
- Molecular Weight:199.29
108-91-8
625 suppliers
$10.00/5mL
49761-82-2
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$5.00/1g
3712-40-1
14 suppliers
$265.00/2.5g
Yield:3712-40-1 92%
Reaction Conditions:
with Imidazole hydrochloride in water at 20; for 0.166667 h;
Steps:
Synthesis of 1-morpholino-2-phenyl ethanone
General procedure: In a round bottomed flask 0.01 mol (1.36 g) phenyl acetic acid and 0.012 mol (1.94 g) of CDI were added. The reaction mixture was mixed and grinded with a spatula. CO2 gas starts releasing with increase in temperature and solid reaction mixture was turned to pale yellow liquid within 5 min. 0.001 mol (0.1 g) Imidazole. hydrochloride, 0.01 mol (0.87 g) of morpholine, and 1 mL of water were added to it. The reaction mixture was kept at room temperature for another 10 min. Dilute hydrochloride solution was added to it and the aqueous layer was washed with ethyl acetate. The organic layer was dried over anhydrous Na2SO4 and concentrated to give pure product.
References:
Verma, Sanjeev K.;Ghorpade, Ramarao;Pratap, Ajay;Kaushik [Tetrahedron Letters,2012,vol. 53,# 19,p. 2373 - 2376] Location in patent:experimental part
24424-99-5
861 suppliers
$13.50/25G
108-91-8
625 suppliers
$10.00/5mL
3712-40-1
14 suppliers
$265.00/2.5g
24424-99-5
861 suppliers
$13.50/25G
19573-22-9
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inquiry
3712-40-1
14 suppliers
$265.00/2.5g
24424-99-5
861 suppliers
$13.50/25G
87100-15-0
113 suppliers
$9.00/1g
3712-40-1
14 suppliers
$265.00/2.5g
4248-19-5
381 suppliers
$5.00/5g
110-82-7
766 suppliers
$10.00/25g
3712-40-1
14 suppliers
$265.00/2.5g