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ChemicalBook CAS DataBase List TERT-BUTYL 3-FORMYLPYRIDIN-4-YLCARBAMATE
116026-93-8

TERT-BUTYL 3-FORMYLPYRIDIN-4-YLCARBAMATE synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 75 percent / tetrahydrofuran / 1 h / Ambient temperature
2: 67 percent / 1.) tert-butyllithium / tetrahydrofuran; pentane / 1.) -78 deg C, 15 min, -20 deg C, 1.5 h, 2.) -15 deg C to room temperature

References:

Venuti, Michael C.;Stephenson, Robert A.;Alvarez, Robert;Bruno, John J.;Strosberg, Arthur M. [Journal of Medicinal Chemistry,1988,vol. 31,# 11,p. 2136 - 2145]

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