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ChemicalBook CAS DataBase List Tacrolimus

104987-11-3

Tacrolimus synthesis

4synthesis methods

Product Name:Tacrolimus
CAS Number:104987-11-3
Molecular formula:C44H69NO12
Molecular Weight:804.02

15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-19-hydroxy-14,16-dimethoxy-3-[2-[3-methoxy-4-[(triethylsilyl)oxy]cyclohexyl]-1-methylethenyl]-4,10,12,18-tetramethyl-8-(2-propenyl)-5-[(triethylsilyl)oxy]-, [3S-[3R*[E(1S*,3S*,4S*)],4R*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-

118977-96-1
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Tacrolimus

104987-11-3
586 suppliers
$31.00/50mg

-

Yield:104987-11-3 100%

Reaction Conditions:

with hydrogen fluoride in acetonitrile at 20; for 0.05 h;

References:

Murakami, Yoshihiro;Kuroda, Akio;Osoda, Kazuhiko;Nishimura, Shintaro [Tetrahedron Letters,2003,vol. 44,# 4,p. 641 - 644]

24,32-Bis-O-(tert-butyldimethylsilyl)-FK-506

133941-75-0
13 suppliers
$139.90/2mg

Tacrolimus

104987-11-3
586 suppliers
$31.00/50mg

3H-Pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,19,20,21(4H,8H,23H)-pentone, 15-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5,6,11,12,13,14,15,16,17,18,24,25,26,26a-tetradecahydro-14,16-dimethoxy-3-[2-[3-methoxy-4-[[tris(1-methylethyl)silyl]oxy]cyclohexyl]-1-methylethenyl]-4,10,12,18-tetramethyl-8-(2-propenyl)-5-[[tris(1-methylethyl)silyl]oxy]-, [3S-[3R*[E(1S*,3S*,4S*)],4R*,5R*,8S*,9E,12R*,14R*,15R*,16R*,18S*,26aR*]]-

128685-18-7
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Tacrolimus

104987-11-3
586 suppliers
$31.00/50mg

197250-11-6 Synthesis

3H-Pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,19,20,21(4H,8H,23H)-pentone, 15-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-[(1E)-2-[(1R,3R,4R)-4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-3-methoxycyclohexyl]-1-methylethenyl]-5,6,11,12,13,14,15,16,17,18,24,25,26,26a-tetradecahydro-5-hydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,26aS)-

197250-11-6
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Tacrolimus

104987-11-3
586 suppliers
$31.00/50mg

Tacrolimus Related Search:

N-LAUROYL-L-ALANINE N-LAUROYLSARCOSINE Ethyl 1-methylpipecolinate Pimecrolimus TETRAHYDRO-2-(2-PROPYNYLOXY)-2H-PYRAN 1-METHYLPIPERIDINE-2-CARBOXYLIC ACID HYDROCHLORIDE

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