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ChemicalBook CAS DataBase List rosoxacin
40034-42-2

rosoxacin synthesis

5synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 4 steps
1: 91 percent / 0.13 h / 130 °C
2: 75 percent / various solvent(s) / 0.2 h / Heating; heating in Dowtherm
3: 45 percent / 1) potassium carbonate / dimethylformamide / 1) 60 deg C, 15 min; 2) stirring 1 h;
4: 89 percent / aq. 10percent KOH / 1 h / Heating

References:

Carabateas;Brundage;Gelotte;et al. [Journal of Heterocyclic Chemistry,1984,vol. 21,# 6,p. 1857 - 1863]

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