ChemicalBook CAS DataBase List Resorcinol

Resorcinol synthesis

15synthesis methods

Product Name:Resorcinol
CAS Number:108-46-3
Molecular formula:C6H6O2
Molecular Weight:110.11

87199-18-6 Synthesis

87199-18-6
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$5.00/250mg

108-46-3
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$10.00/10g

Yield:108-46-3 98%

Reaction Conditions:

with oxygen;triethylamine in 2-methyltetrahydrofuran at 20; under 760.051 Torr; for 48 h;UV-irradiation;

Steps:

2 3. Preferred embodiment

General procedure: [1,1'-Biphenyl] -4-phenylboronic acid (59.4mg, 0.3mmol, 1.0equiv) was added to a dried 20mL quartz test tube,Vacuum the quartz test tube while backfilling with oxygen three times.Under oxygen conditions, Et3N (62.5 L, 0.45 mmol, 1.5 equiv) and 2-methyltetrahydrofuran (4 ml) were sequentially added through a syringe.The resulting mixture was stirred for 5 minutes, then the quartz test tube was transferred to a photoreactor.The test tube was placed about 2 cm from the 15W UV lamp.The reaction mixture was stirred and illuminated for 24 h,After the specified time, the crude product was diluted with ethyl acetate, filtered through a pad of silica gel, and concentrated under reduced pressure.Flash chromatography on silica gel was then performed directly on silica gel (EtOAc / PE = 1/10) to give the desired product 1b (92% yield, white solid).

References:

CN110668921,2020,A Location in patent:Paragraph 0025-0028; 0030-0032

150-19-6 Synthesis