ChemicalBook CAS DataBase List 3-Aminophenol

3-Aminophenol synthesis

14synthesis methods

Product Name:3-Aminophenol
CAS Number:591-27-5
Molecular formula:C6H7NO
Molecular Weight:109.13

3-Amino-2-cyclohexene-1-one (1.5 mol, 166.7 g), potassium acetate (6 mmol, 0.6 g), and 5% palladium on carbon (4.7 g, 65.5% water) were added to N, N-dimethylacetamide (475 g) solvent in one liter creased round bottom flask equipped with a nitrogen purge, thermometer, condenser, distillation head, overhead stirrer, and heating mantle. The solution was then heated to reflux for two hours at 173° C. with a continuous nitrogen purge. The palladium catalyst was filtered from the solution. Gas chromatography analysis indicated 130.9 g 3-aminophenol (1.2 mole, 80% yield based on 3-amino-2-cyclohexene-1-one).

554-84-7
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591-27-5
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$11.00/10g

Yield:591-27-5 100%

Reaction Conditions:

with hydrogen in ethanol at 60; under 7500.75 Torr; for 2 h;

Steps:

6 Example 6

The nanocomposite material prepared in Preparation Example 1 was used as a catalyst for the hydrogenation reduction reaction of nitrophenol compounds.Should, the specific experimental steps are: 0.1g of nanocomposite material, 0.33g of m-nitrophenol, 30mL of ethanol were added to the reaction kettle, and H2 replacement reactionAfter responding to the kettle 3 times, pass H2 again to make the pressure in the reactor 1MPa, stir and raise the temperature to the predetermined reaction temperature of 60C, continueAfter 2 hours of reaction, the heating was stopped, the pressure was discharged after the temperature was reduced to room temperature, the reaction kettle was opened and the product m-aminophenol was taken out for chromatographic analysis.The conversion rate of reactants, product selectivity and TOF were calculated by the formula shown in Example 1, and the conversion rate of m-nitrophenol was obtained.Is 100%, the selectivity of m-aminophenol is 99.2%, and the TOF is 8.41 X 10-3s-

References:

CN111470989,2020,A Location in patent:Paragraph 0097-0101; 0149-0151