ChemicalBook CAS DataBase List (R)-(-)-1,2,3,4-Tetrahydro-1-naphthylamine

(R)-(-)-1,2,3,4-Tetrahydro-1-naphthylamine synthesis

10synthesis methods

Product Name:(R)-(-)-1,2,3,4-Tetrahydro-1-naphthylamine
CAS Number:23357-46-2
Molecular formula:C10H13N
Molecular Weight:147.22

(R)-1-Amino-1,2,3,4-tetrahydronaphthalene is a contactor that can be synthesized by the reaction of an enantiomerically pure amine with a primary oxidant.

2217-40-5 Synthesis

2217-40-5
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$10.00/1g

298-12-4 Synthesis

298-12-4
455 suppliers
$5.00/25g

(R)-(-)-1,2,3,4-Tetrahydro-1-naphthylamine

23357-46-2
160 suppliers
$7.00/1g

529-34-0 Synthesis

529-34-0
486 suppliers
$6.00/10g

Yield:> 99 % ee

Reaction Conditions:

with pyridoxal 5'-phosphate;recombinant ω-transaminase from Burkholderia vietnamiensis G4 in aq. buffer at 37; pH=7.4; for 12 h;Resolution of racemate;Enzymatic reaction;enantioselective reaction;

Steps:

2.9. Kinetic resolution of racemic amines

General procedure: Racemic amine (10 mM, Table 4) was mixed with glyoxylate (10 mM) in 1 ml of phosphate buffer (100 mM, pH 7.4) containing PLP (20 μM). The reaction was started by adding 0.8 mg/ml of HBV-ω-TA, and the mixture was incubated at 37 °C for 12 h. The amount and ee value of the residual amino donor were determined according to Section 2.10.

References:

Jiang, Jinju;Chen, Xi;Feng, Jinhui;Wu, Qiaqing;Zhu, Dunming [Journal of Molecular Catalysis B: Enzymatic,2014,vol. 100,p. 32 - 39]

529-34-0 Synthesis

529-34-0
486 suppliers
$6.00/10g

23357-52-0 Synthesis