ChemicalBook CAS DataBase List P-TOLYL ACETATE

P-TOLYL ACETATE synthesis

14synthesis methods

Product Name:P-TOLYL ACETATE
CAS Number:140-39-6
Molecular formula:C9H10O2
Molecular Weight:150.17

By acetylation of p-cresol.

106-44-5 Synthesis

106-44-5
476 suppliers
$14.00/5g

75-36-5 Synthesis

75-36-5
567 suppliers
$17.92/100G

140-39-6
199 suppliers
$10.00/25g

Yield:140-39-6 99%

Reaction Conditions:

with trifluorormethanesulfonic acid in acetonitrile at 20; for 1 h;

Steps:

4.2. General procedure for O-acylation of phenols in TfOH
General procedure: Phenol (0.28 mmol) and acyl chloride (0.84 mmol, 3 equiv) were dissolved in 1% TfOH/CH₃CN (1 ml) at room temperature. The reaction mixture was stirred at same temperature for an hour, then poured into cold water and ethyl acetate. The organic layer was washed with 1 M HCl, saturated NaHCO₃, and saturated NaCl, and dried over MgSO₄, then filtered. The filtrate was concentrated to afford O-acylated products. All spectral data were identical with the literatures.^[27]^,^27(a)^,^27(b)^,^27(c)^,^27(d)^,^27(e)^,^27(f)^,^27(g)^and^27(h)

References:

Murashige, Ryo;Hayashi, Yuka;Ohmori, Syo;Torii, Ayuko;Aizu, Yoko;Muto, Yasuyuki;Murai, Yuta;Oda, Yuji;Hashimoto, Makoto [Tetrahedron,2011,vol. 67,# 3,p. 641 - 649] Location in patent:experimental part

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106-44-5 Synthesis

106-44-5
476 suppliers
$14.00/5g

64-19-7 Synthesis