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ChemicalBook CAS DataBase List N-TRIFLUOROACETYL-L-PHENYLALANINE
350-09-4

N-TRIFLUOROACETYL-L-PHENYLALANINE synthesis

13synthesis methods
-

Yield:350-09-4 99%

Reaction Conditions:

with triethylamine in methanol at 20;

Steps:

General Procedure for the Preparation of TFA-a-Amino Acid

General procedure: The corresponding amino groups ofα-amino acid underwent TFA protection by using ethyl trifluoroacetate in the presence of triethylamine in MeOH to generate TFA-α-amino acid (L-/D-2, L-/D-15, L-/D-20, see Supplementary Information)

References:

Tachrim, Zetryana Puteri;Oida, Kazuhiro;Ohashi, Fumina;Wakasa, Haruna;Ikemoto, Haruka;Kurokawa, Natsumi;Sakihama, Yasuko;Hashidoko, Yasuyuki;Suzuki, Takeyuki;Hashimoto, Makoto [Heterocycles,2018,vol. 97,# 2,p. 877 - 893]

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