ChemicalBook CAS DataBase List N-TERT-BUTYLACRYLAMIDE

N-TERT-BUTYLACRYLAMIDE synthesis

10synthesis methods

Product Name:N-TERT-BUTYLACRYLAMIDE
CAS Number:107-58-4
Molecular formula:C7H13NO
Molecular Weight:127.18

540-88-5
365 suppliers
$21.00/25mL

107-13-1 Synthesis

107-13-1
406 suppliers
$16.00/25ML

107-58-4
210 suppliers
$7.00/10g

Yield:107-58-4 95%

Reaction Conditions:

with BF₃ immobilized on β-cyclodextrine functionalized silica coated CoFe₂O₄ magnetic nanoparticles in neat (no solvent) at 20; for 0.5 h;Ritter Amidation;

Steps:

2.4. General procedure for the modified-Ritter reaction catalyzed byCoFe2O4(at)SiO2-PrNH-βCDs-BF3
General procedure: A mixture of tertbutyl acetate (2.5 mmol), nitirle (1 mmol), andCoFe2O4SiO2-NH-βCDs-BF3 (0.08 g) was stirred in neat conditiontill completion of the reaction (monitored by TLC). After reactioncompletion, CH2Cl2 was added to the reaction mixture and theorganic layer was simply decanted by means of an external magnet.Then, the reaction mixture was extracted with CH2Cl2, driedover Na2SO4, concentrated under vacuum and the pure productwas obtained. This was further purified by recrystallization withsuitable solvent (EtOAc/hexane). Melting point, 1H NMR, 13CNMR and FT-IR spectra were consistent with the assigned structuresin literature [43,62,63].

References:

Hamadi, Hosein;Zanjani, Zohreh;Yadollahi, Mahtab [Polyhedron,2020,vol. 175,art. no. 114219]

FullText

24424-99-5 Synthesis