N-CHLOROACETANILIDE synthesis
- Product Name:N-CHLOROACETANILIDE
- CAS Number:579-11-3
- Molecular formula:C8H8ClNO
- Molecular Weight:169.61
103-84-4
347 suppliers
$12.00/100g
579-11-3
41 suppliers
$155.00/100mg
Yield: 98.9%
Reaction Conditions:
with hypochlorous anhydride;sodium hydroxide at 15 - 30; for 5 h;Reagent/catalyst;Temperature;
Steps:
1-6 Example 5
500ml with thermometer and mechanical agitation300.14g of purified water was added to the reaction flask.4.42 g of sodium hydroxide was added to the reaction flask.Adding acetanilide 50.02g,Dichlorine monoxide is introduced into the reaction flask,The amount of nitrous oxide introduced was 20.9 g.Heat the reaction at 15 ~ 30 ° C for 5 hours,FilteredN-chloroacetanilide,Drying to a solid of 62.92g,The purity of the solid is 98.7%.The molar yield was 98.9%.
References:
Shandong Guobang Pharmaceutical Co., Ltd.;Guobang Pharmaceutical And Chemical Group Co., Ltd.;Da Xianpeng;Li Qibin;Wang Weihong CN109400495, 2019, A Location in patent:Paragraph 0020-0043
507-40-4
131 suppliers
$144.00/25g
103-84-4
347 suppliers
$12.00/100g
579-11-3
41 suppliers
$155.00/100mg
62-53-3
660 suppliers
$10.00/1g
579-11-3
41 suppliers
$155.00/100mg
7782-50-5
2 suppliers
$373.00/454g
64-19-7
1564 suppliers
$10.00/25ML
103-84-4
347 suppliers
$12.00/100g
533-17-5
154 suppliers
$7.00/5g
579-11-3
41 suppliers
$155.00/100mg
539-03-7
314 suppliers
$10.00/5 g
127-09-3
1081 suppliers
$8.00/1 ea
7782-50-5
2 suppliers
$373.00/454g
64-19-7
1564 suppliers
$10.00/25ML
103-84-4
347 suppliers
$12.00/100g
533-17-5
154 suppliers
$7.00/5g
579-11-3
41 suppliers
$155.00/100mg
539-03-7
314 suppliers
$10.00/5 g