ChemicalBook CAS DataBase List N-(4-CHLOROPHENYL)-2-NITROBENZENAMINE

N-(4-CHLOROPHENYL)-2-NITROBENZENAMINE synthesis

4synthesis methods

Product Name:N-(4-CHLOROPHENYL)-2-NITROBENZENAMINE
CAS Number:23008-56-2
Molecular formula:C12H9ClN2O2
Molecular Weight:248.67

4-Chlorobenzenamine and 1-Chloro-2-nitrobenzene?condensation

106-47-8 Synthesis

106-47-8
475 suppliers
$5.00/5G

1493-27-2
512 suppliers
$5.00/10g

23008-56-2
100 suppliers
$10.00/250mg

Yield:23008-56-2 96%

Reaction Conditions:

with triethylamine in neat (no solvent) at 140; for 9 h;

Steps:

General procedure for the synthesis of 3 in Table 3

General procedure: A mixture of 1-fluoro-2-nitrobenzene 1 (1.5 g, 11 mmol), 2 (16 mmol), and triethylamine (0.6 g, 5.5 mol) was stirred at 140 °C for 9 h. After completion of the reaction as indicated by TLC, the mixture was cooled to 20 °C and filtered. The filter cake was washed with water and anhydrous ethanol until the pH of filtrate reached 7, then dried in vacuum to obtain compound 3.

References:

Cui, Jian-Lan;Wang, Ning;Wang, Xiao;Yu, Si-Yuan;Zhong, Cong-Shan [Tetrahedron Letters,2020,vol. 61,# 11] Location in patent:supporting information

106-47-8 Synthesis

106-47-8
475 suppliers
$5.00/5G

88-73-3 Synthesis