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ChemicalBook CAS DataBase List 2-Nitrophenylboronic acid
5570-19-4

2-Nitrophenylboronic acid synthesis

7synthesis methods
-

Yield:5570-19-4 99%

Reaction Conditions:

with nitric acid;N,N-dimethyl-formamide;sodium nitrite at 45;Reagent/catalyst;Solvent;Temperature;

Steps:

6 Example 6:

Nitric acid (126 g, 2 mol) and sodium nitrite (0.04 mol) were added dropwise, and the reaction temperature was controlled at 45 °C, and the reaction mixture was stirred and reacted with dimethylformamide (15 mol). Completely poured into ice water, concentrated to a small volume, cooling, standing, until the solid precipitation, Filtration, ice water washing, collecting product 165.3g, molar yield 99.0%, HPLC greater than 99.5%.

References:

CN104788484,2017,B Location in patent:Paragraph 0026-0039

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