METHYL 2,4-DINITROPHENYLACETATE synthesis
6synthesis methods
- Product Name:METHYL 2,4-DINITROPHENYLACETATE
- CAS Number:58605-12-2
- Molecular formula:C9H8N2O6
- Molecular Weight:240.17
Yield:58605-12-2 100%
Reaction Conditions:
in methanol;toluene at 20; for 3 h;
Steps:
B.1
22.6 g (100 mmol) of 2,4-dinitrophenylacetic acid is dissolved in a mixture of 200 ml of methanol and 830 ml of toluene, mixed at room temperature with 83 ml of trimethylsilyldiazomethane (2 molar in toluene; 166 mmol) and stirred for 3 hours at room temperature. After concentration by evaporation to the dry state and drying at 70° C. in a vacuum, 24 g (100 % of theory) of 2,4-dinitrophenyl-acetic acid methyl ester is obtained
References:
US2004/39019,2004,A1 Location in patent:Page/Page column 5-6