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ChemicalBook CAS DataBase List Isoamyl acetate
123-92-2

Isoamyl acetate synthesis

13synthesis methods
By the esterification of commercial isoamyl alcohol with acetic acid
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Yield:123-92-2 95%

Reaction Conditions:

with iron zirconium phosphate in neat (no solvent) at 40; for 0.166667 h;Green chemistry;

Steps:

General experimental procedure for the acetylation of substrates under solvent-free conditions

General procedure: ZPFe (1 mol%) was added to a mixture of alcohol (1 mmol) and AA (2 mmol), and the resulting mixture was stirred at 40 °C for a specified time (Scheme 2). Upon completion of the reaction (as determined by gas chromatography), the catalyst was separated from the reaction mixture by centrifuge, after which the supernatant was collected and diluted with a 10% NaHCO3 solution (10 mL) before being extracted with Et2O (2 × 10 mL).The combined organic extracts were washed and then dried over anhydrous CaCl2 before being evaporated to dryness under vacuum to give the desired product. In some cases, it was necessary to purify the product by column chromatography ona silica gel column with elution by a mixture of cyclohexane and ethyl acetate

References:

Hajipour, Abdol R.;Karimi, Hirbod;Masti, Amir [Chinese Journal of Catalysis,2015,vol. 36,# 4,p. 595 - 602]

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